Results 61 to 70 of about 46,515 (282)
ChemistryOpen, EarlyView.Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali +4 more
wiley +1 more source
Mosquito Larvicidal Constituents from Lantana Viburnoides SP Viburnoides Var Kisi (A. rich) Verdc (Verbenaceae). [PDF]
, 2008 \ud \ud Lantana viburnoides sp viburnoides var kisi is used in Tanzania ethnobotanically to repel mosquitoes as well as in traditional medicine for stomach ache relief.
Gikonyo, Nicholus K +5 more
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Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Molecules, 2022 Dendritic cells are antigen-presenting cells, which identify and process pathogens to subsequently activate specific T lymphocytes. To regulate the immune responses, DCs have to mature by the recognition of TLR ligands, TNFα or IFNγ.
Gabriela Piñón-Zárate +9 more
doaj +1 more source
Triterpene Production in Centella Asiatica (L.) Urban (Pegaga) Callus and Cell Suspension Cultures [PDF]
, 2004 Centella asiatica or locally known as ‘Pegaga’ is one of the most common medicinal plants used by diverse ancient cultures and tribal groups. Its medicinal values are mainly attributed to the presence of the triterpene constituents.
Ling, Anna Pick Kiong
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A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules [PDF]
, 2017 Plants are an excellent source of drug leads. However availability is limited by access to source species, low abundance and recalcitrance to chemical synthesis.
Alain Goossens +57 more
core +2 more sources
Phytotherapy Research, EarlyView.ABSTRACT Chronic atrophic gastritis (CAG), a widespread gastrointestinal condition, is widely acknowledged as a precursor to gastric cancer (GC). The incidence of CAG has been steadily increasing, yet effective pharmacological interventions remain unavailable. Asiatic acid (AA), a bioactive triterpenoid isolated from Centella asiatica, has demonstrated
Feifei Zhou +9 more
wiley +1 more source
From 2000 years of Ganoderma lucidum to recent developments in nutraceuticals [PDF]
, 2015 Medicinal mushrooms have been used for centuries as nutraceuticals to improve health and to treat numerous chronic and infectious diseases. One such mushroom is Ganoderma lucidum, commonly known as Lingzhi, a species revered as a medicinal mushroom for ...
Bishop, Karen S. +5 more
core +1 more source
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function
Phytotherapy Research, EarlyView.Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng +8 more
wiley +1 more source
Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum [PDF]
, 2009 Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations.
Hirasawa, Yusuke +6 more
core +1 more source