Results 161 to 170 of about 62,766 (245)

Fucoidan: An Update on Function, Role in Human Health and Applications

Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
Fucoidan is a promising bioactive compound with anti‐inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, thanks to its epigenetic potential, ability to modulate autophagic mechanisms and possibility adjuvant agent or bioactive component of the drug delivery systems, fucoidan is a promising ...
Sharon Critelli, Marilena Celano
wiley   +1 more source

Phytochemical small molecules from <i>Stauntonia chinensis</i> DC as multi-target modulators: molecular mechanisms and therapeutic potential. [PDF]

Am J Transl Res
Cheng F, Wang SM, Xiao M, Zhou H, Chen B, Zhang QH.   +5 more
europepmc   +1 more source

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source

Aqueous bio-based hydrotropic solutions for green extraction of glycyrrhizic acid from licorice: experimental investigation and mechanistic insights. [PDF]

RSC Adv
Le NT, Thi Phan HT, Tran TH, Nguyen HT, Nguyen HT.   +4 more
europepmc   +1 more source

Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3032-3047, May 2026.
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim, Keunhwa Kim, Jung Heo, Seung Mo Seo, Sungjun Choung, Hyeonjin Kim, Yuri Choi, Kyungsun Park, Hyejung Yun, Dongha Kim, Eun Song Lee, Junwoo Lee, Smita Mirsyad Warsadiharja, Saet Buyl Lee, Sunkyu Han, Soon Ju Park, Sang‐Gyu Kim   +16 more
wiley   +1 more source

Study on the tissue-specific distribution of triterpenoid saponins in <i>Panax japonicus</i> var. <i>major</i> based on metabolomics and transcriptomics. [PDF]

Open Life Sci
Wang Z, Xu Y, Li Y, Zhang D, Song X, Huang W.   +5 more
europepmc   +1 more source

Chromosome‐Scale Haplotype Genome Assemblies for the Australian Mango ‘Kensington Pride’ and a Wild Relative, Mangifera laurina, Provide Insights Into Anthracnose‐Resistance and Volatile Compound Biosynthesis Genes

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3172-3188, May 2026.
ABSTRACT Mango (Mangifera indica) is one of the most popular fruits cultivated in tropical and subtropical regions of the world. The availability of reference genomes helps to identify the genetic basis of important traits. Here, we report assembled high‐quality chromosome‐level genomes for the Australian mango cultivar ‘Kensington Pride’ and M ...
Upendra Kumari Wijesundara, Agnelo Furtado, Ardashir Kharabian Masouleh, Natalie L. Dillon, Heather E. Smyth, Robert J. Henry   +5 more
wiley   +1 more source

RETRACTED: Ikram et al. Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions. <i>Cells</i> 2021, <i>10</i>, 2719. [PDF]

Cells
Ikram M, Ikram M, Jo MH, Choe K, Khan A, Ahmad S, Saeed K, Kim MW, Kim MO.   +8 more
europepmc   +1 more source

Correction: Integrated metabolome and transcriptome analysis identifies candidate genes involved in triterpenoid saponin biosynthesis in leaves of <i>Centella asiatica</i> (L.) Urban. [PDF]

Front Plant Sci
Wan L, Huang Q, Li C, Yu H, Tan G, Wei S, El-Sappah AH, Sooranna S, Zhang K, Pan L, Zhang Z, Lei M.   +11 more
europepmc   +1 more source

<i>Centella asiatica</i> as a Model Biomass for Sustainable Production of Biochemicals via Green Extraction and Purification Technologies: A Comprehensive Field-to-Market Review. [PDF]

Molecules
Razzaq W, Mazzitelli JB, Fabiano Tixier AS, Vian MA.   +3 more
europepmc   +1 more source