Results 31 to 40 of about 30,032 (223)
Melanoma is one of the most dangerous forms of skin cancer, characterized by early metastasis and rapid development. In search for effective treatment options, much attention is given to triterpenoids of plant origin, which are considered promising drug ...
Marta Grudzińska +4 more
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Covering: 2013. Previous review: Nat. Prod. Rep., 2015, 29, 1028–1065 This review covers the isolation and structure determination of triterpenoids reported during 2013 including squalene derivatives, lanostanes, holostanes, cycloartanes, cucurbitanes,
Connolly, Joseph D., Hill, Robert A.
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Determination of the Five Main Terpenoids in Different Tissues of Wolfiporia cocos
Wolfiporia cocos is a fungus containing triterpenoids and is widely used as an herbal medicine. However, it is unknown whether its main triterpenoid contents differ in different tissues.
Ming Fu +5 more
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This review covers the isolation and structure determination of triterpenoids including squalene derivatives, protostanes, lanostanes, holostanes, cycloartanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, lupanes, oleananes, friedelanes ...
Hill, R.A., Connolly, J.D.
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Antifeedant Triterpenoids from the Seeds and Bark of Lansium domesticum cv Kokossan (Meliaceae)
Two tetranortriterpenoids, kokosanolide A (1) and C (2) were isolated from the seeds and three onoceranoid-type triterpenoids: kokosanolide B (3), 8,14-secogammacera-7,14-diene-3,21-dione (4) and a 1.5:0.5 mixture of 8,14-secogammacera-7,14(27)-diene-3 ...
Roekmiati Tjokronegoro +5 more
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Triterpenoids widely exist in nature, displaying a variety of pharmacological activities. Determining triterpenoids in different matrices, especially in biological samples holds great significance. High-performance liquid chromatography (HPLC) has become
Xiao-Feng Huang +5 more
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Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu +11 more
wiley +1 more source
Antrodia camphorata (AC) is a precious medicinal mushroom native to Taiwan and famous for its excellent pharmacological activity. A ball mill assisted mechanochemical extraction method was applied in the extraction of triterpenoids from Antrodia ...
Rongjun He +4 more
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Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
Bioactive triterpenoids from Salvia species
Salvia species are important medicinal and culinary plants, and they have been the subject of numerous chemical and biological studies. The bioactive triterpenoids of Salvia species, reported in the literature to date, are reviewed.
Topcu, G
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