Results 111 to 120 of about 44,808,645 (302)

In Situ Monitoring of Morphology Changes and Oxygenation State of Human Erythrocytes During Surfactant-Induced Hemolysis

Cells
Erythrocytes, the most abundant blood cells, are a prevalent cell model for the analysis of the membrane-damaging effects of different molecules, including drugs.
Miroslav Karabaliev, Boyana Paarvanova, Gergana Savova, Bilyana Tacheva, Radostina Georgieva   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Direct UV Spectrophotometry and HPLC Determination of Triton X-100 in Split Virus Influenza Vaccine

, 2016
One of the most commonly used surfactants in the production of split virus influenza vaccine is nonionic surfactant Triton X-100. After splitting of the virus is accomplished, Triton X-100 is removed from the vaccine by subsequent production steps ...
Dragacević, Luka, Vujić, Zorica, Pavlović, Bojana, Ivković, Branka, Cvijetić, Nataša, Kuntić, Vesna   +5 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Photophysical and photochemical properties of triton X-165 in aqueous and methanolic solutions

, 1994
Laser flash photolysis of the nonionic surfactant Triton X-165 was carried out at 248 nm in methanolic and aqueous solutions at different pHs. Cation radical, triplet, phenoxy radical and solvated electron were observed as the transient absorbing species.
Ramarao, K. V. S., Ghosh, H. N., Sapre, A. V., Palit, D. K., Mittal, J. P.   +4 more
core   +1 more source

对峙反应的胶束催化研究

四川大学学报. 自然科学版, 2000
Applying characteristic parameter method of thermokinetics for 2 2 type opposing reactions, thermokinetics of the opposing reaction of nitroethane with trihydroxymethyl aminomethane in cetyltrimethylammonium bromide(CTAB), sodium dodcyl sulfate(SDS) and ...
程四清, 陈晓楠, 孟祥光, 陈勇, 张元勤, 曾宪诚   +5 more
doaj  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Spectroscopic study of the ternary complex of beta-cyclodextrin, pyrene, and triton X-100

, 1993
The increased fluorescence intensity of pyrene due to indirect excitation by the nonionic surfactant Triton X-100 is discussed. Sensitization is quantitatively shown to occur in mixed solutions of pyrene, Triton X-100, and β-cyciodextrin (β-CD).
Warner, Isiah M., Ndou, Thilivhali T., Smith, Vonda K., Cummings, Elizabeth A.   +3 more
core   +1 more source

Cytotoxic effects of Triton X-100 on Allium Cepa L [PDF]

, 2012
Yüksek Lisans TeziBu çalışmada, bir noniyonik surfaktan(yüzey aktif madde) olan Triton X-100’ün farklı konsantrasyonlarının Allium cepa L.’nın kök uçlarında kök büyümesi, mitotik indeks, mitotik faz indeksi ve kromozom aberasyonları üzerindeki etkileri ...
Öztürk, Fatmanur
core   +1 more source