Results 121 to 130 of about 44,808,645 (302)

Identification of compendial nonionic detergents for the replacement of Triton X-100 in bioprocessing. [PDF]

open access: yesBiotechnol Prog, 2022
Hunter AK   +8 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Liquid–Liquid Equilibrium of Aqueous Two-Phase Systems Formed by Nonionic Surfactants (Triton X‑100, Triton X‑165, or Triton X‑305), Salts (NaNO3 or KNO3), and Water at Different Temperatures

open access: yes
Liquid–liquid equilibrium data for aqueous two-phase systems (ATPSs) formed by nonionic surfactants (Triton X-100, Triton X-165, or Triton X-305), inorganic salts (NaNO3 or KNO3), and water were obtained at 298.2, 313.2, or 328.2 K.
Aparecida Barbosa Mageste (11617553)   +5 more
core   +1 more source

Perinuclear KV10.1 is resistant to Triton X-100 extraction.

open access: yes, 2013
CHO cells transfected with KV10.1-mVenus were incubated without (A) or with (B) 3% Triton X-100 for 5 min, fixed and analyzed by confocal microscopy. Triton X-100 largely extracted the cytoplasmic signal, while the perinuclear signal was still detected ...
Tobias Kohl (254238)   +5 more
core   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Ability of membTF mutants to support FVIIa amidolytic activity and FX activation in solution (with 0.1% Triton X-100).

open access: yes, 2014
Ability of membTF mutants to support FVIIa amidolytic activity and FX activation in solution (with 0.1% Triton X-100).
Jian Yuan (585683)   +2 more
core   +1 more source

Serum Triton-X 100 treatment does not affect individual serum bile acid levels

open access: yesJournal of Laboratory Medicine
Triton X-100 is a nonionic surfactant used for solvent/detergent viral inactivation, disrupting lipid-enveloped viruses while preserving proteins. At 1 % in plasma, it inactivates SARS-CoV-2 within 10 min with ≥6 log10 titer reduction and is compatible ...
Harnisch Lars-Olav   +2 more
doaj   +1 more source

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