Results 91 to 100 of about 2,385,649 (308)
Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling [PDF]
Molecular and Cellular Neuroscience, 2016 Neurotrophins, essential regulators of many aspects of neuronal differentiation and function, signal via four receptors, p75, TrkA, TrkB and TrkC. The three Trk paralogs are members of the LIG superfamily of membrane proteins, which share extracellular domains consisting of leucine-rich repeat and C2 Ig domains.
James S, Meabon +7 more
openaire +2 more sources
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Involvement of TRK receptors in the nootropic effect of cycloprolylglycine
Фармакокинетика и ФармакодинамикаBackground. The neuropeptide cycloprolylglycine (CPG) is an endogenous dipeptide analogue of the nootropic piracetam. It has been experimentally shown that CPG (designed and synthesized at the Federal State Budgetary Scientific Institution «Federal ...
O. N. Vorontsova +5 more
doaj +1 more source
Effects of Eight Weeks of Resistance Exercises on Expression of Neurotrophins and Trk Receptors in Alzheimer Model Male Wistar Rats [PDF]
, 2021 Gholamhasan Jafarzadeh +3 more
openalex +1 more source
From mechanism to phenotype: What fits in a basket trial
Epilepsia, EarlyView.
Kette D. Valente
wiley +1 more source
WHO classification of skin tumours: key updates in the fifth edition
Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy +29 more
wiley +1 more source
Accumulation of the Drosophila Torso-like protein at the blastoderm plasma membrane suggests that it translocates from the eggshell [PDF]
, 2015 © 2015. Published by The Company of Biologists Ltd. The eggshell serves as a depository for proteins that play an important role in early embryonic development.
Casanova, Jordi +2 more
core +3 more sources
Macromolecular Bioscience, Volume 26, Issue 1, January 2026.Kaur–Trautmann et al. present a high‐throughput, chemically defined 3D glioblastoma model based on glycosaminoglycan hydrogels that allow orthogonal control of stiffness, adhesion, and degradability while standardizing soluble‐factor presentation. The platform supports automated imaging and transcriptomic profiling, enabling patient‐specific drug ...
Rajvinder Kaur Trautmann +9 more
wiley +1 more source
Kidins220/ARMS as a functional mediator of multiple receptor signalling pathways [PDF]
, 2012 An increasing body of evidence suggests that several membrane receptors – in addition to activating distinct signalling cascades – also engage in substantial crosstalk with each other, thereby adjusting their signalling outcome as a function of specific ...
Benfenati, Fabio +3 more
core +1 more source
The effect of P75 on Trk receptors in neuroblastomas [PDF]
Cancer Letters, 2011 Neuroblastomas (NBs) with favorable outcome usually express TrkA, whereas unfavorable NBs frequently express TrkB and its cognate ligand BDNF. P75 (p75(LNTR), NGFR, TNFRSF16) binds NGF-related neurotrophins with low affinity and usually is coexpressed with Trk receptors in NBs. Here, we investigated the importance of p75 coexpression with Trk receptors
Ruth, Ho +6 more
openaire +2 more sources