Results 131 to 140 of about 2,385,649 (308)

The Trk Potassium Transporter Is Required for RsmB-Mediated Activation of Virulence in the Phytopathogen Pectobacterium wasabiae [PDF]

open access: yes, 2015
Pectobacterium wasabiae (previously known as Erwinia carotovora) is an important plant pathogen that regulates the production of plant cell wall-degrading enzymes through an N-acyl homoserine lactone-based quorum sensing system and through the GacS/GacA ...
Valente, Rita S., Xavier, Karina Bivar
core   +1 more source

The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration [PDF]

open access: yes, 2015
NMDA Receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL Receptor-related Protein-1 (LRP1) to trigger cell-signaling in response to protein ligands in neurons.
Campana, W. Marie   +4 more
core   +2 more sources

Spatio-temporal control of neurotrophin trafficking and signalling in primary neurons cultured inside microfluidic chambers

open access: yes, 2011
My PhD project was aimed at applying microfluidics technology to the study of longrange neurotrophin signalling. Neurotrophins are target-derived growth and survival factors that, among other functions, prevent innervating neurons from undergoing ...
Menendez, Guillermo, Menendez, Guillermo
core   +1 more source

NTRK amplification occurs frequently in pan-TRK immunopositive dedifferentiated liposarcomas

open access: yesPathology and Oncology Research
The neurotrophic tyrosine kinase receptor (NTRK) gene family is of rising importance as their fusions are oncogenic, and specific target drugs are available to inhibit the chimera proteins.
Zoltán Lippai   +5 more
doaj   +1 more source

[18F]TRACK, a PET tracer for imaging of tropomyosin receptor kinases (Trk): efficient radiosynthesis and preliminary evaluation in the TgF344‐AD rat model of Alzheimer’s disease. [PDF]

open access: bronze, 2022
Min Su Kang   +11 more
openalex   +1 more source

Boosting pancreatic cancer chemotherapy by disrupting nerve–cancer crosstalk

open access: yesActa Materia Medica
A preclinical study has developed a precision nano-intervention strategy targeting tumor-associated nerves to destroy nerve-fueled tumor growth in pancreatic cancer.
Yutian Xia, Jianzhong Zhang
doaj   +1 more source

Fyn-Mediated Regulation of Protein Kinase A [PDF]

open access: yes, 2017
Protein kinases are enzymes important for signal transduction in the regulation of cellular processes. The cAMP-dependent protein kinase A (PKA) has been previously reported to regulate the activity of the Src family kinase Fyn, an event important for ...
Barritt, Sam
core   +1 more source

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