Results 151 to 160 of about 2,385,649 (308)

Tyrosine kinase A, C and fibroblast growth factor-2 receptors in bovine embryos cultured in vitro [PDF]

, 2013
Neurotrophins and basic fibroblast growth factor are ligands of tyrosine kinase receptors, though they bind to different tyrosine kinase receptor classes.
Caamaño, J.N. (José), Díez, C., Facal, Nieves, Fernández-Sánchez, M.T. (M.), Frutos, C., Gómez, E., Muñoz, M., Pérez-Gómez, A., Rodríguez, A.   +8 more
core  

EPV038/#163 Neurotrophic tyrosine kinase receptor-1 (NTRK-1) rearranged cervical sarcoma with fibrosarcoma like morphology presenting in a 13-year-old managed with a neo-adjuvant trk-inhibitor and surgical excision [PDF]

, 2021
Elizabeth A Goulding, Philip Morreau, Mandy De Silva, Michael Watson, Betty Leung, Claire van Vliet, Lucian Eva   +6 more
openalex   +1 more source

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models

Cell Reports
Summary: Pediatric-type high-grade gliomas frequently harbor gene fusions involving receptor tyrosine kinase genes, including neurotrophic tyrosine kinase receptor (NTRK) fusions.
Sebastian Schmid, Zachary R. Russell, Alex Shimura Yamashita, Madeline E. West, Abigail G. Parrish, Julia Walker, Dmytro Rudoy, James Z. Yan, David C. Quist, Betemariyam N. Gessesse, Neriah Alvinez, Kimberly D. Hill, Larry W. Anderson, Patrick J. Cimino, Debra K. Kumasaka, Ralph E. Parchment, Eric C. Holland, Frank Szulzewsky   +17 more
doaj   +1 more source

Syntheses of 10-Oxo, 10.ALPHA.-Hydroxy, and 10.BETA.-Hydroxy Derivatives of a Potent .KAPPA.-Opioid Receptor Agonist, TRK-820

, 2004
Hiromasa Horikiri, Noriyuki Hirano, Yoichiro Tanaka, Junji Oishi, Hitoshi Hatakeyama, Kuniaki Kawamura, Hiroshi Nagase   +6 more
openalex   +2 more sources

High prevalence of NTRK fusions in sporadic dMMR/MSI mCRC RAS/RAF wild-type: an opportunity for a post-immune checkpoint inhibitors progression rescue strategy

ESMO Gastrointestinal Oncology
Background: Currently, mismatch repair deficient/microsatellite instable (dMMR/MSI) status constitutes a validated predictive marker of response to immune checkpoint inhibitors (ICIs) in patients with metastatic colorectal cancer (mCRC).
M. Svrcek, A. Cayre, T. Samaille, R. Colle, L. Mas, P. Bourgoin, E. Guillerm, R. Cohen, F. Penault-Llorca, T. André, N. Radosevic-Robin   +10 more
doaj   +1 more source

NGF Binding to the trk Tyrosine Kinase Receptor Requires the Extracellular Immunoglobulin-like Domains

, 1995
Pilar Pérez, Pedro M. Coll, Barbara L. Hempstead, Dionisio Martín‐Zanca, Moses V. Chao   +4 more
openalex   +1 more source

Larotrectinib in NTRK3 fusion–positive metastatic secretory carcinoma of the breast: A case study

Current Problems in Cancer: Case Reports
Triple-negative breast cancer (TNBC) is an aggressive heterogeneous form of breast cancer that accounts for 15 %-20 % of all breast cancers. Characterized by an absence of estrogen receptor, progesterone receptor, and human epidermal growth factor ...
Martin Dietrich, Michel Velez
doaj   +1 more source

Heterodimeric Neurotrophins Induce Phosphorylation of Trk Receptors and Promote Neuronal Differentiation in PC12 Cells [PDF]

, 1995
James Treanor, Charles H. Schmelzer, Beat Knüsel, John Winslow, David L. Shelton, Franz Hefti, Károly Nikolics, Louis E. Burton   +7 more
openalex   +1 more source

Generalization of NMDA-Receptor Antagonists to the Discriminative Stimulus Effects of κ-Opioid Receptor Agonists U-50,488H, but Not TRK-820 in Rats

, 2006
Tomohisa Mori, Mutsuko Nomura, Kazumi Yoshizawa, Hiroshi Nagase, Toshiko Sawaguchi, Minoru Narita, Tsutomu Suzuki   +6 more
openalex   +2 more sources

Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation [PDF]

, 2000
Dominique Melck
openalex   +1 more source