Results 241 to 250 of about 2,385,649 (308)

Novel Insights Into Receptor Tyrosine Kinases in Pulmonary Arterial Hypertension. [PDF]

J Am Heart Assoc
Wu W, Kong F, Chen Z, Huang L, Nie X, Bian JS.   +5 more
europepmc   +1 more source

TRK Inhibitors in Adult and Pediatric High-Grade Gliomas: A Systematic Review and Individual Participant Data Meta-Analysis. [PDF]

Cancers (Basel)
Rizzaro MD, Fanizzi C, Fiore G, Remore LG, Ampollini AM, Pluderi M, Caroli M, Locatelli M.   +7 more
europepmc   +1 more source

Case Report: Dramatic response to entritinib in a patient with gastrointestinal stromal tumor positive for <i>NTRK3</i> fusion. [PDF]

Front Oncol
Dong G, Han P, Zhang Z, Ge Q, Jiang J, Li S, Ma J, Bai J, Wei H, Zhao Z.   +9 more
europepmc   +1 more source

Application of Wuling powder in the treatment of ulcerative colitis complicated by depression as a new therapy principle. [PDF]

World J Gastroenterol
Smirnova OV, Sinyakov A, Kasparov EV.
europepmc   +1 more source

Identification of the neurotrophin receptors p75 and trk in a series of Wilms' tumors.

, 1994
M Donovan, Barbara L. Hempstead, L.Julie Huber, David R. Kaplan, Pantelis Tsoulfas, Moses V. Chao, Luis F. Parada, Deborah E. Schofield   +7 more
openalex   +1 more source

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The TrK Receptor Family

, 2015
The Trk family is composed of three principal members (A, B and C), also termed neurotrophin tyrosine kinase receptors (NTRK1, NTRK2, NTRK3), with several additional splice variants, which in humans are located on three different chromosomes (1, 9, 15).
H. Hondermarck, Y. Demont, R. Bradshaw
semanticscholar   +2 more sources

Ubiquitin Regulation of Trk Receptor Trafficking and Degradation

Molecular Neurobiology, 2018
The regulation of Trk receptors is critical for orchestrating multiple signalling pathways required for developing and maintaining neuronal networks. Activation of Trk receptors results in signalling, internalisation and subsequent degradation of the protein.
S. Murray, A. W. Wong, J. Yang, Y. Li, U. Putz, S. Tan, J. Howitt   +6 more
semanticscholar   +4 more sources

Neurotrophin signal transduction by the Trk receptor.

Journal of Neurobiology, 1994
AbstractThe initial event in the neuronal differentiation of PC12 cells is the binding of the neurotrophin nerve growth factor (NGF) to the Trk receptor. This interaction stimulates the intrinsic tyrosine kinase activity of TRk, initiating a signalling cascade involving the phosphorylation of intracellular proteins on tyrosine, serine, and threonine ...
D. Kaplan, R. Stephens
semanticscholar   +3 more sources