Results 1 to 10 of about 358,649 (401)

tRNA signatures reveal polyphyletic origins of streamlined SAR11 genomes among the alphaproteobacteria [PDF]

, 2013
Phylogenomic analyses are subject to bias from compositional convergence and noise from horizontal gene transfer (HGT). Compositional convergence is a likely cause of controversy regarding phylogeny of the SAR11 group of Alphaproteobacteria that have extremely streamlined, A+T-biased genomes.
Amrine, Katherine C. H., Ardell, David H., Swingley, Wesley D.   +2 more
arxiv   +6 more sources

Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation [PDF]

, 2009
Determining the mechanism by which transfer RNAs (tRNAs) rapidly and precisely transit through the ribosomal A, P and E sites during translation remains a major goal in the study of protein synthesis. Here, we report the real-time dynamics of the L1 stalk, a structural element of the large ribosomal subunit that is implicated in directing tRNA ...
Chris H. Wiggins, Jake M. Hofman, Jingyi Fei, Jonathan E. Bronson, Moran, Rathi L. Srinivas, Ruben L. Gonzalez   +6 more
arxiv   +6 more sources

Electron microscopic visualization of tRNA genes with ferritin-avidin: biotin labels [PDF]

, 1978
A method is described for indirect electron microscopic visualization and mapping of tRNA and other short transcripts hybridized to DNA. This method depends upon the attachment of the electron-dense protein ferritin to the RNA, the binding being mediated
Angerer, Lynne M., Broker, Thomas R., Davidson, Norman, Hershey, N. Davis, Yen, Pauline H.   +4 more
core   +3 more sources

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes [PDF]

J. Mol. Evol. 64 (2007) 662-688, 2007
Many cases of non-standard genetic codes are known in mitochondrial genomes. We carry out analysis of phylogeny and codon usage of organisms for which the complete mitochondrial genome is available, and we determine the most likely mechanism for codon reassignment in each case. Reassignment events can be classified according to the gain-loss framework.
A Reyes, A Schneider, AM Nedelcu, AM Simpson, AP Sibler, BF Lang, C Gissi, CA Lozupone, CE Bullerwell, D Urbina, DH Ardell, DV Lavrov, DW Schultz, DW Schultz, E Seif, E Talla, EM Denovan-Wright, FHC Crick, G Burger, G Burger, G Burger, H Asahara, HS Kim, J Castrasena, J Matsugi, J Swire, JD Alfonzo, JL Blanchard, JL Boore, K Hancock, K Tomita, Knight, Knight, M Ehara, M Ehara, M Kimura, M Nohara, M Turmel, MAS Santos, MAS Santos, ME Saks, MJ Laforest, MJ Telford, MV Sanchez Puerta, N Spruyt, NJ Savill, Paul G. Higgs, PG Higgs, PG Higgs, PJ Keeling, PS Lovett, R Giegé, R Koszul, RC Morris, S Kerscher, S Matsuyama, S Osawa, S Osawa, S Osawa, S Sengupta, S Yokobori, SE Massey, SG Andersson, SG Andersson, SJ Freeland, Supratim Sengupta, T Muramatsu, Tomita, Tomita, U Kück, Xiaoguang Yang, Y Hayashi-Ishimaru, Y Hayashi-Ishimaru, Y Inagaki, Y Kuchino   +74 more
arxiv   +7 more sources

Dovednost učitele motivovat žáka [PDF]

Pedagogická Orientace, 2018
N ...
Josef Trna
doaj   +2 more sources

The Triplet Genetic Code had a Doublet Predecessor [PDF]

Journal of Theoretical Biology 233 (2005) 527-532, 2004
Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and anticodons $\overleftarrow{\rm GNN}$. Evidence for this scenario is presented based on the properties of aminoacyl-tRNA
Patel, Apoorva
arxiv   +2 more sources

Breaking the genetic code – a new revolutionary stage in the development of molecular biology: 1968 Nobel Prize laureates M. W. Nirenberg, H. G. Khorana, R. W. Holley [PDF]

The Ukrainian Biochemical Journal, 2021
This review presents the life stories of M. Nirenberg, H. Khorana, and R. Holley, winners of the 1968 Nobel Prize in Physiology or Medicine, the history of the discoveries made by these scientists, and the methodological approaches used in their works ...
O. P. Matyshevska, V. M. Danilova, S. V. Komisarenko   +2 more
doaj   +1 more source

The tRNA identity landscape for aminoacylation and beyond

Nucleic Acids Research, 2023
tRNAs are key partners in ribosome-dependent protein synthesis. This process is highly dependent on the fidelity of tRNA aminoacylation by aminoacyl-tRNA synthetases and relies primarily on sets of identities within tRNA molecules composed of ...
R. Giegé, G. Eriani
semanticscholar   +1 more source

METTL1 promotes hepatocarcinogenesis via m7G tRNA modification‐dependent translation control

Clinical and Translational Medicine, 2021
Background N7‐methylguanosine (m7G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular mechanism of m7G tRNA modification in hepatocellular carcinoma (HCC) remain poorly understood ...
Zhi-hang Chen, Wanjie Zhu, S. Zhu, K. Sun, Junbin Liao, Haining Liu, Zihao Dai, Hui Han, Xuxin Ren, Qingxia Yang, Siyi Zheng, B. Peng, S. Peng, M. Kuang, Shuibin Lin   +14 more
semanticscholar   +1 more source

Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes [PDF]

Open Biology, 2017
RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA. The originally defined yeast Pol III transcriptome appears to be expanding owing to the application of new methods.
Ewa Leśniewska, Magdalena Boguta
doaj   +1 more source