Results 121 to 130 of about 234,592 (250)

Učební úlohy ve výuce fyziky na 2. stupni základní školy: vybrané výsledky CPV videostudie fyziky

open access: yesPedagogická Orientace, 2008
Učební úlohy představují soubor specifických požadavků kladených na žákovo učení. Z hlediska didaktiky je klíčovou otázka, jaký potenciál mají učební úlohy pro procesy učení. Předkládané výzkumné sdělení je zaměřeno právě tímto směrem.
I. Vaculová, J. Trna, T. Janík
doaj  

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki   +10 more
wiley   +1 more source

[Altmayer, Claus. Kulturstudien : eine Einführung für das Fach Deutsch als Fremd- und Zweitspracheg]

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2023
Johannes Köck, Jan Trna
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Optimization of expression and purification of atypical arginyl-tRNA-synthetases

open access: yes
Arginil-tRNA-sintetaza (ArgRS) je enzim koji katalizira nastajanje arginil-tRNA, supstrata za biosintezu proteina, u dva koraka: aktivacija arginina pomoću ATP-a te njegovo prenošenje na tRNAArg.
Knežević, Karla
core   +2 more sources

tRNA as an assembly chaperone for a macromolecular transcription-processing complex

open access: yes
Transfer RNAs (tRNAs) are widely recognized for their role in translation. Here, we describe a previously unidentified function of tRNA as an assembly chaperone.
Zimmermann, Johannes Patrick   +12 more
core   +1 more source

Vaginal host–microbe signatures linked to placental outcomes in mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule   +7 more
wiley   +1 more source

细胞分化中的tRNA修饰现象

open access: yes, 1986
<正> Kersten和Katze等人的实验表明,真菌、粘菌和脊椎动物癌组织的细胞分化过程中存在着tRNA的核苷酸被修饰的现象。修饰发生在某些tRNA特定的位置上。tRNA~(Asn)、tRNA~(Asp)、tRNA~(His)和tRNA~(Tyr)的反密码子第一位(第34号位)的鸟苷(G)被queosine(Q)代替。Q是鸟嘌呤的嘌呤骨架修饰成一个7-去氮结构,它的化学名称应叫7-(4,5-顺式-二羟-2 ...
孙建民
core  

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