Results 111 to 120 of about 234,592 (250)
Characterization of leucyl-TRNA synthetase from homo sapiens and escherichia coli in aminoacylation, amino acid editing and interdomain interactions [PDF]
Aminoacyl-tRNA synthetases (aaRSs) are ancient enzymes that charge tRNA with its cognate amino acid. In order to maintain fidelity during protein synthesis, editing mechanisms ensure that tRNAs are accurately charged. Leucyl-tRNA synthetase (LeuRS) has
Pang, Yan Ling Joy
core
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Koordinace vzdělávacích cílů v Občanské a Základní škole
N ...
Josef Trna, Eva Trnová
doaj
Assessment of Attainable Distances in Proteins by Through‐Space 19F–19F Couplings
De novo synthesized difluorinated tryptophan analogues are site‐specifically incorporated into Cyclophilin A (CypA). 19F–19F NOESY build‐up experiments are recorded for each labeled protein, and the distances derived from cross‐relaxation rates are compared to reference distances.
Iker Hernández +6 more
wiley +1 more source
Development of an in vivo tryptofanyl-tRNA synthetase inhibition assay
Aminoacil-tRNA-sintetaze (AaRS), predstavljaju dobru metu za razvoj novih antibiotika, jer postoje značajne razlike između evolucijski očuvanih prokariotskih i eukariotskih enzima.
Subota, Kristian
core +2 more sources
Das Regensburger Symposium : ein Bericht
Jan Trna
doaj +1 more source
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi +6 more
wiley +1 more source
In Sloterdijks Weltinnenraum : ein Konferenzbericht
Jan Trna
doaj +1 more source
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
wiley +1 more source

