Results 91 to 100 of about 234,592 (250)
Nuclear and mitochondrial tRNA-lookalikes in the human genome
Frontiers in Genetics, 2014 We are interested in identifying and characterizing loci of the human genome that harbor sequences resembling known mitochondrial and nuclear tRNAs. To this end, we used the known nuclear and mitochondrial tRNA genes (the tRNA-Reference set) to search ...
Aristeidis G Telonis +3 more
doaj +1 more source
L‐Cysteine and N‐Acetylcysteine Supplementation Improves Clinical Outcome in a Patient With COXPD10
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT MTO1 is a nuclear gene that encodes a mitochondrial protein essential for modifying mitochondrial transfer RNAs (tRNAs) and stabilizing codon‐anticodon interactions to ensure accurate and efficient mitochondrial protein synthesis and oxidative phosphorylation.
Nishitha R. Pillai +5 more
wiley +1 more source
, 2016 The functionality of small RNAs from abundant species of "housekeeping" noncoding RNAs (e.g., rRNA, tRNA, snRNA, snoRNA, etc.) remains a highly studied topic.
Andrew Sobala +15 more
core +1 more source
Cysteinyl-tRNA formation and prolyl-tRNA synthetase [PDF]
, 2002 Aminoacyl-tRNA (AA-tRNA) formation is a key step in protein biosynthesis. This reaction is catalyzed with remarkable accuracy by the AA-tRNA synthetases, a family of 20 evolutionarily conserved enzymes. The lack of cysteinyl-tRNA (Cys-tRNA) synthetase in
Jacquin-Becker, Clarisse +11 more
core +1 more source
Human Retrovirus Codon Usage from tRNA Point of View: Therapeutic Insights
, 2013 The purpose of this study was to investigate the balance between transfer ribonucleic acid (tRNA) supply and demand in retrovirus-infected cells, seeking the best targets for antiretroviral therapy based on the hypothetical tRNA Inhibition Therapy (TRIT).
Vagner S. Fonseca +16 more
core +1 more source
ND4/tRNA-His/tRNA-Ser/tRNA-Leu/ND5 Alignment
, 2009 ND4/tRNA-His/tRNA-Ser/tRNA-Leu/ND5 ...
Trevor Jones (3258114) +6 more
core +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source