Results 211 to 220 of about 345,668 (351)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

open access: yesVIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao   +6 more
wiley   +1 more source

High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma

open access: green, 2009
Ying Zhou   +4 more
openalex   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

open access: yesVIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie   +9 more
wiley   +1 more source

Glutamyl-tRNA reductase from Escherichia coli and Synechocystis 6803. Gene structure and expression.

open access: hybrid, 1992
Elizabeth Verkamp   +4 more
openalex   +1 more source

Biological functions of tsRNAs and research advances in human disease. [PDF]

open access: yesBiochem Biophys Rep
Jiang Y   +9 more
europepmc   +1 more source

Therapeutic Efficacy of the Supersulfide Donor NAC‐S2 in Influenza Virus Pneumonia via Suppression of Excessive Inflammatory Responses

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Influenza pneumonia is characterized by excessive inflammatory responses that contribute to severe lung injury and mortality. Supersulfides, endogenously produced cysteine‐derived persulfides and polysulfides, exert potent antioxidant, anti‐ferroptotic, and anti‐inflammatory activities; however, their therapeutic potential after disease onset ...
Foysal Hossen   +9 more
wiley   +1 more source

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