Results 241 to 250 of about 404,299 (351)

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

open access: yesMed Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang   +13 more
wiley   +1 more source

Quantitative CRACI reveals transcriptome-wide distribution of RNA dihydrouridine at base resolution. [PDF]

open access: yesNat Commun
Ju CW   +21 more
europepmc   +1 more source

Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5′ tRNA-Val-CAC-2-1 Half

open access: gold, 2019
Joseph M. Dhahbi   +11 more
openalex   +1 more source

Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs

open access: yesNature Chemistry, 2018
Julian C. W. Willis, J. Chin
semanticscholar   +1 more source

Breast Milk Proteome: Changes in the Different Stages of Lactation and Impacts of Gestational Diabetes Mellitus and Body Mass Index

open access: yesMolecular Nutrition &Food Research, EarlyView.
We analyzed colostrum and breast milk from 47 mothers to see how proteins change over time and with maternal health. Colostrum had more immune proteins, while mature milk had proteins linked to growth support. Gestational diabetes and higher BMI altered the protein composition.
Timo Seitz   +9 more
wiley   +1 more source

Dad's Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health

open access: yesMolecular Nutrition &Food Research, EarlyView.
This review highlights the emerging connection between paternal nutrition‐induced sperm epigenetic changes and placental phenotypes that may influence offspring metabolic health. An accompanying interactive ShinyApp allows exploration of these sperm–placenta gene networks, a framework for future research seeking to explore candidate biomarkers or ...
David A. Skerrett‐Byrne   +6 more
wiley   +1 more source

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