Results 261 to 270 of about 345,668 (351)

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

open access: yesBiological Reviews, EarlyView.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto   +3 more
wiley   +1 more source

Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors

open access: green, 2019
Wenhe Zhong   +18 more
openalex   +2 more sources

Homoharringtonine Promotes FTO Degradation to Suppress LILRB4‐Mediated Immune Evasion in Acute Monocytic Leukaemia

open access: yesCell Proliferation, EarlyView.
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang   +18 more
wiley   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

open access: yesCell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long   +6 more
wiley   +1 more source

A dual‐specific Glu‐tRNAGln and Asp‐tRNAAsn amidotransferase is involved in decoding glutamine and asparagine codons in Acidithiobacillus ferrooxidans

open access: green, 2001
Juan Carlos Salazar   +5 more
openalex   +2 more sources

Evolutionary taxonomy and conservation status of environmentally sensitive and endangered musk deer (Moschus spp.): An updated review

open access: yesConservation Science and Practice, EarlyView.
This study reviews the historical taxonomic classification and evolutionary background of musk deer, clarifying long‐standing confusion in their identification. It highlights the current global distribution and conservation status of these species, emphasizing the threat posed by poaching and habitat destruction. The work aims to raise public awareness
Zhirong Zhang   +7 more
wiley   +1 more source

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