Results 261 to 270 of about 404,299 (351)

Multidirectional in silico and in vitro Research for the Pharmaceutical Potential of Fibigia Clypeata (L.) Medik: Phytochemical, Antimicrobial, and Antimyeloma Properties

ChemistryOpen, EarlyView.
Fibigia clypeata water extract has a slightly more substantial inhibitory effect than the methanol extract. F. clypeata decreased cell viability in three human MM cells and the MCF10A cell lines. Cyanidin 3‐rutinoside chloride has the highest binding affinity to Staphylococcus aureus MurB, Candida parapsilosis, and Candida albicans dihydrofolate ...
Tuba Unver, Ugur Uzuner, Dilara Akcora‐Yildiz, Ismet Gurhan, Caglar Arkan, Zeynep Ozdemir   +5 more
wiley   +1 more source

Nanopore sequencing of intact aminoacylated tRNAs. [PDF]

Nat Commun
White LK, Radakovic A, Sajek MP, Dobson K, Riemondy KA, Del Pozo S, Szostak JW, Hesselberth JR.   +7 more
europepmc   +1 more source

Enjoy the Silence: Nearly Half of Human tRNA Genes Are Silent [PDF]

, 2019
Adrián Gabriel Torres
openalex   +1 more source

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

PROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland, Luke A. Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Emily J. Sunnucks, Sam T. Gould, Aleksandra M. Stanczak, Matthew B. O'Rourke, Matthew P. Padula   +9 more
wiley   +1 more source

ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation. [PDF]

Cancer Discov
Shen C, Che Y, Zhou K, Wang K, Li W, Xue D, Wu T, Yang L, Chen M, Sheng Y, Zhang C, Robinson S, Chen H, Sau L, Chen Z, Wunderlich M, Han L, Tang T, Qing Y, Wu D, Sun M, Leung K, Dąbrowska K, Pirrotte P, Hu YC, Ghoda LY, Zhang B, Mulloy JC, Wei M, Marcucci G, He C, Deng X, Chen J.   +32 more
europepmc   +1 more source

Key Considerations on CITE‐Seq for Single‐Cell Multiomics

PROTEOMICS, EarlyView.
ABSTRACT CITE‐Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) is an advanced single‐cell sequencing method to profile both gene expression and protein abundance simultaneously in individual cells using single‐cell mRNA sequencing techniques alongside antibody‐derived tags (ADTs), for protein detection.
Hye‐Wong Song, Jody Martin, Xiaoshan Shi, Aaron J. Tyznik   +3 more
wiley   +1 more source

Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons. [PDF]

Nat Commun
Dong L, Wang J, Xia Q.
europepmc   +1 more source

ARWEN: a program to detect tRNA genes in metazoan mitochondrial nucleotide sequences

Bioinform., 2008
D. Laslett, Björn Canbäck
semanticscholar   +1 more source

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Identification of novel RNA polymerase III promoters in bovine leukemia virus miRNA cluster by cross-taxa analysis of small non-coding RNAs. [PDF]

BMC Genomics
Pluta A, Droscha C.
europepmc   +1 more source