Results 281 to 290 of about 324,922 (336)

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

open access: yesThe FEBS Journal, EarlyView.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer   +8 more
wiley   +1 more source

The quest for the best target genes for RNAi‐mediated pest control

open access: yesInsect Molecular Biology, EarlyView.
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley   +1 more source

Uncertainty‐Aware Visualization of Biomolecular Structures

open access: yes
Computer Graphics Forum, EarlyView.
A. Sterzik   +3 more
wiley   +1 more source

Multi‐omics analysis reveals discordant proteome and transcriptome responses in larval guts of Frankliniella occidentalis infected with an orthotospovirus

open access: yesInsect Molecular Biology, EarlyView.
Tomato spotted wilt virus modulated the abundance of gut proteins in larval thrips, most notably manifested as a predominant down‐regulation in first instar larvae. Gut‐expressed protein and cognate transcript abundance were moderately correlated across the tissue system; however, the virus effect varied widely at transcriptional and translational ...
Jinlong Han, Dorith Rotenberg
wiley   +1 more source

Expanded ribosomal synthesis of non-standard cyclic backbones in vitro. [PDF]

open access: yesNat Commun
Lee K   +5 more
europepmc   +1 more source

Origin, Divergence and Migration Routes of Psyllids of the Cacopsylla pruni Complex (Hemiptera: Psylloidea) Inferred by Approximate Bayesian Computation Methods

open access: yesJournal of Biogeography, EarlyView.
ABSTRACT Aim Population genetics is essential to decipher the evolutionary history of pests and insect vectors from both a theoretical point of view and to predict and mitigate the future of epidemics. We attempt to shed light on the evolutionary history and phylogeography of two cryptic psyllid species (namely, A and B) of the Cacopsylla pruni complex,
Margaux Darnis   +2 more
wiley   +1 more source

tRNA binding to Kti12 is crucial for wobble uridine modification by Elongator. [PDF]

open access: yesNucleic Acids Res
Scherf D   +6 more
europepmc   +1 more source

Temperature‐dependent alterations in the proteome of the emergent fish pathogen Edwardsiella piscicida

open access: yesJournal of Fish Diseases, EarlyView.
Abstract Edwardsiella piscicida is an emerging bacterial pathogen and the aetiological agent of edwardsiellosis among cultured and wild fish species globally. The increased frequency of outbreaks of this Gram‐negative, facultative intracellular pathogen pose not only a threat to the aquaculture industry but also a possible foodborne/waterborne public ...
Kim L. Jacobsen   +7 more
wiley   +1 more source

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