Results 291 to 300 of about 404,299 (351)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

ICE<i>Cle</i>SHZ29: Novel Integrative and Conjugative Element (ICE)-Carrying Tigecycline Resistance Gene <i>tet</i>(X6) in <i>Chryseobacterium lecithinasegens</i>. [PDF]

open access: yesAntibiotics (Basel)
Chen X   +14 more
europepmc   +1 more source

Optimizing (Bio) Catalysis with Liquid‐Liquid Phase Separation Systems

open access: yesChemSystemsChem, EarlyView.
This review highlights how LLPS creates membraneless compartments involved in different scenarios in nature. It further explores different examples that focus on the development of synthetic coacervates that enhance catalytic efficiency by concentrating reactants, or by the direct influence of the coacervates building blocks themselves.
David Q. P. Reis   +4 more
wiley   +1 more source

Deciphering epigenetic regulation in postmenopausal osteoporosis: Current and future perspectives

open access: yesVIEW, EarlyView.
In this perspective, the significant roles of microRNAs, long noncoding RNAs and circular RNAs in postmenopausal osteoporosis are thoroughly expounded. The advantages and limitations of typical noncoding RNAs as diagnostic biomarkers and therapeutic targets are summarized and discussed.
Xiumei Tang   +10 more
wiley   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

A proliferation associated tRNA regulatory nexus on human chromosome 6 plays a central role in cell state-dependent gene expression

open access: yes
Bushell M   +10 more
europepmc   +1 more source

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