Results 291 to 300 of about 241,053 (344)

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

open access: yesIntegrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong   +7 more
wiley   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

open access: yesIntegrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu   +8 more
wiley   +1 more source

Refining the Vertebrate Mitochondrial 12S rRNA Secondary Structure by Comparative Analysis

open access: yesIntegrative Zoology, EarlyView.
This flowchart outlines the comprehensive workflow of the study, integrating diverse bioinformatics tools (e.g., NCBI2GO, SSU‐align, bpRNA) and their sequential interactions. Key steps, such as data preprocessing, structural prediction, and evolutionary analysis, are depicted with their respective outputs (e.g., standardized records, consensus ...
Fengxia Li   +6 more
wiley   +1 more source

"Bei Kafka ist nach wie vor vieles neu, immer noch." : Interview mit Bernhard Setzwein über seinen Roman

open access: yesBrünner Beiträge zur Germanistik und Nordistik
Jan Trna, Bernhard Setzwein
doaj  
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tRNA dysregulation and disease

open access: yesNature Reviews Genetics, 2022
Esteban A Orellana, Richard I Gregory
exaly   +2 more sources

Action mechanisms and research methods of tRNA-derived small RNAs

open access: yesSignal Transduction and Targeted Therapy, 2020
tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or precursor tRNAs.
Junming Guo
exaly   +2 more sources

Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading

open access: yesNature, 2020
Ribosomes accurately decode mRNA by proofreading each aminoacyl-tRNA that is delivered by the elongation factor EF-Tu 1 . To understand the molecular mechanism of this proofreading step it is necessary to visualize GTP-catalysed elongation, which has ...
Anna B Loveland   +2 more
exaly   +2 more sources

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