Results 31 to 40 of about 345,668 (351)

The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution [PDF]

open access: yes, 2008
Maturation of tRNA precursors into functional tRNA molecules requires trimming of the primary transcript at both the 5' and 3' ends. Cleavage of nucleotides from the 3' stem of tRNA precursors, releasing nucleotide diphosphates, is accomplished in ...
Blagova, Elena V.   +5 more
core   +2 more sources

"Wenn mans zum ersten Mal hört, dann verchlüpft man automatisch." : eine Gratwanderung zwischen Sterbehelfer und Mörder : essayistische Überlegungen zu Alices Reise in die Schweiz von Lukas Bärfuss

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2022
This essay deals with the stage play "Alices Reise in die Schweiz" (Alice's trip to Switzerland) by Lukas Bärfuss, specifically focusing on the main character Gustav.
Jan Trna
doaj   +1 more source

Aminoacyl-tRNA synthetases [PDF]

open access: yesRNA, 2020
The aminoacyl-tRNA synthetases are an essential and universally distributed family of enzymes that plays a critical role in protein synthesis, pairing tRNAs with their cognate amino acids for decoding mRNAs according to the genetic code. Synthetases help to ensure accurate translation of the genetic code by using both highly accurate cognate substrate ...
Miguel Angel Rubio Gomez, Michael Ibba
openaire   +3 more sources

Principles of Palliative and Supportive Care in Pancreatic Cancer: A Review

open access: yesBiomedicines, 2023
Pancreatic adenocarcinoma (PDAC) is well known for its poor survival time. Clinical symptoms are painless jaundice or abdominal or back pain. Less specific symptoms often appear that make diagnosis difficult, e.g., weight loss, loss of appetite, nausea ...
Robert Mazur, Jan Trna
doaj   +1 more source

Aminoacyl-tRNA synthetase-induced cleavage of tRNA

open access: yesNucleic Acids Research, 1992
Aminoacyl-tRNA synthetases interact with their cognate tRNAs in a highly specific fashion. We have examined the phenomenon that upon complex formation E. coli glutaminyl-tRNA synthetase destabilizes tRNA(Gln) causing chain scissions in the presence of Mg2+ ions. The phosphodiester bond cleavage produces 3'-phosphate and 5'-hydroxyl ends.
S, Beresten, M, Jahn, D, Söll
openaire   +3 more sources

tRNA-tRNA interactions within cellular ribosomes. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1989
We describe an assay that converts the effects of tRNA-tRNA contacts at two particular codons into a quantitative effect on beta-galactosidase level. The assay measures the separate and combined efficiency of suppression at adjacent nonsense codons in vivo using a set of specially created homologous messages.
D, Smith, M, Yarus
openaire   +2 more sources

Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 simultaneously binds Glutamyl-Prolyl-tRNA synthetase and scaffold protein aminoacyl tRNA synthetase complex interacting multifunctional protein 3 of the multi-tRNA synthetase complex [PDF]

open access: yes, 2018
Higher eukaryotes have developed extensive compartmentalization of amino acid (aa) - tRNA coupling through the formation of a multi-synthetase complex (MSC) that is composed of eight aa-tRNA synthetases (ARS) and three scaffold proteins: aminoacyl tRNA ...
Bartlett, Seamus   +2 more
core   +1 more source

Initiator tRNA genes template the 3' CCA end at high frequencies in bacteria. [PDF]

open access: yes, 2016
BackgroundWhile the CCA sequence at the mature 3' end of tRNAs is conserved and critical for translational function, a genetic template for this sequence is not always contained in tRNA genes.
Ardell, David H, Hou, Ya-Ming
core   +3 more sources

Drugging tRNA aminoacylation [PDF]

open access: yesRNA Biology, 2018
Inhibition of tRNA aminoacylation has proven to be an effective antimicrobial strategy, impeding an essential step of protein synthesis. Mupirocin, the well-known selective inhibitor of bacterial isoleucyl-tRNA synthetase, is one of three aminoacylation inhibitors now approved for human or animal use.
Joanne M. Ho   +3 more
openaire   +2 more sources

Evaluační standardy ve fyzikálním vzdělávání. [PDF]

open access: yes, 2004
Evaluační standardy fyzikálního vzdělávání jsou klíčovou součástí inovované vzdělávací technologie výuky na základních a středních školách. Článek se zabývá definováním, funkcí a tvorbou těchto standardů.Evaluation standards of physics education are the ...
Trna Josef
core  

Home - About - Disclaimer - Privacy