Results 161 to 170 of about 55,541 (288)

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Functions of Bacterial tRNA Modifications: From Ubiquity to Diversity. [PDF]

Trends Microbiol, 2021
de Crécy-Lagard V, Jaroch M.
europepmc   +1 more source

A cell-free plant extract for accurate pre-tRNA processing, splicing and modification. [PDF]

, 1987
Nicole Stange, H. Beier
openalex   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Additional file 2: of Identification of tRNA nucleoside modification genes critical for stress response and development in rice and Arabidopsis

, 2017
Youmei Wang, Chaoqun Pang, Xukai Li, Zhen Hu, Zhengyi Lv, Bo Zheng, Peng Chen   +6 more
openalex   +1 more source

Codon adaptation to tRNAs with Inosine modification at position 34 is widespread among Eukaryotes and present in two Bacterial phyla [PDF]

, 2017
Àlbert Rafels-Ybern, Adrián Gabriel Torres, Xavier Grau‐Bové, Iñaki Ruiz‐Trillo, Lluı́s Ribas de Pouplana   +4 more
openalex   +1 more source

tRNA queuosine modification enzyme modulates the growth and microbiome recruitment to breast tumors [PDF]

, 2020
Jilei Zhang, Rong Lu, Yongguo Zhang, Żaneta Matuszek, Yinglin Xia, Tao Pan, Jun Sun   +6 more
openalex   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source

tRNA Modifications as a Readout of S and Fe-S Metabolism. [PDF]

Methods Mol Biol, 2021
Edwards AM, Addo MA, Dos Santos PC.
europepmc   +1 more source