Results 171 to 180 of about 55,926 (239)

Decoding the role of tRNA modifications in cancer progression. [PDF]

Curr Opin Genet Dev
Hughes RO, Davis HJ, Nease LA, Piskounova E.   +3 more
europepmc   +1 more source

Misactivation of multiple starvation responses in yeast by loss of tRNA modifications. [PDF]

Nucleic Acids Res, 2020
Bruch A, Laguna T, Butter F, Schaffrath R, Klassen R.   +4 more
europepmc   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source

The importance of tRNA modifications in the brain

The importance of tRNA modifications in the brain
名称：第101回日本生理学会大会 主催：一般社団法人日本生理学会 大会テーマ：生理学のこれから　～生命の多様性と調和～ New Horizon in Physiology – Diversity and Harmony in Life – 大会長：上田 陽一 (産業医科大学) 会期：2024(令和6)年3月28日(木)～30日(土) 会場：北九州国際会議場・西日本総合展示場 (福岡県北九州市小倉北区浅野三丁目 8-1)
openaire  

Snake Gut Microbiota as a Source of Anti‐Inflammatory Probiotics: Isolation and Functional Characterization of Two Novel Strains

Integrative Zoology, EarlyView.
This study assessed the probiotic potential of intestinal microbiomes from five snake species using metagenomics and in vitro isolation, identifying two promising strains (Lactobacillus johnsonii DA0116 and Limosilactobacillus reuteri DA0218) through comprehensive screening.
Xuena Kang, Lan Hu, Jiarong Song, Zhenjie Zhang, Yi Li, Qingqing Zhang, Cuiling Luo, Yu Pang, Peng Guo, Bisong Yue, Ping Li, Zhenxin Fan   +11 more
wiley   +1 more source

Nest Survival Models and Genomics Illuminate Hybridisation Attempts, Guiding Culturally Informed Management to Recover a Critically Endangered Seabird

Animal Conservation, EarlyView.
Long‐term monitoring has revealed hybridisation attempts between the Critically Endangered Kuaka Whenua Hou (KWH, Pelecanoides whenuahouensis) and the abundant Kuaka (P. urinatrix). Here we use modelling based on population monitoring data in tandem with genomic data to investigate these attempts and the risk they pose to KWH recovery.
N. J. Forsdick, T. R. Buckley, T. Davis, I. Debski, J. H. Fischer   +4 more
wiley   +1 more source

Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells.

Blood
Pauli C, Kienhöfer M, Blank MF, Begik O, Rohde C, Zimmermann SMN, Werner L, Heid D, Xu F, Weidenauer K, Delaunay S, Krall N, Trunk K, Zhao D, Zhou F, Llovera L, Ollivier A, Heit-Mondrzyk A, Platzbecker U, Baldus C, Serve H, Bornhäuser M, Vågbø CB, Benitah SA, Krijgsveld J, Novoa EM, Müller-Tidow C, Frye M.   +27 more
europepmc   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

Cancer Science, EarlyView.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

The impact of tRNA modifications on translation in cancer: identifying novel therapeutic avenues. [PDF]

NAR Cancer
Añazco-Guenkova AM, Miguel-López B, Monteagudo-García Ó, García-Vílchez R, Blanco S.   +4 more
europepmc   +1 more source

Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications. [PDF]

Nat Chem Biol, 2020
Kimura S, Dedon PC, Waldor MK.
europepmc   +1 more source