Results 11 to 20 of about 20,098 (205)

A new case of platelet‐type von Willebrand disease supports the recent findings of gain‐of‐function GP1BA variants outside the C‐terminal disulphide loop enhances affinity for von Willebrand factor

British Journal of Haematology, Volume 203, Issue 4, Page 673-677, November 2023., 2023
Summary Platelet‐type von Willebrand disease (PT‐VWD) is a rare autosomal dominant bleeding disorder characterized by an increased ristocetin‐induced platelet aggregation (RIPA) and enhanced affinity of platelet glycoprotein Ibα (GPIbα) to von Willebrand factor (VWF).
Catarina Monteiro, Ana Gonçalves, Mónica Pereira, Catarina Lau, Sara Morais, Rosário Santos   +5 more
wiley   +1 more source

Off‐target effects of oral anticoagulants – vascular effects of vitamin K antagonist and non‐vitamin K antagonist oral anticoagulant dabigatran etexilate

Journal of Thrombosis and Haemostasis, Volume 19, Issue 5, Page 1348-1363, May 2021., 2021
Abstract Introduction Vitamin K antagonists (VKA) and non‐vitamin K oral antagonist anticoagulants (NOAC) are used in the clinic to reduce risk of thrombosis. However, they also exhibit vascular off‐target effects. The aim of this study is to compare VKA and NOAC on atherosclerosis progression and calcification in an experimental setup.
Rick H. van Gorp, Ingrid Dijkgraaf, Vanessa Bröker, Matthias Bauwens, Peter Leenders, Danyel Jennen, Marc R. Dweck, Jan Bucerius, Jacco J. Briedé, Joanne van Ryn, Vincent Brandenburg, Felix Mottaghy, Henri M. H. Spronk, Chris P. Reutelingsperger, Leon J. Schurgers   +14 more
wiley   +1 more source

Barriers to blood donation on social media: An analysis of Facebook and Twitter posts

Transfusion, Volume 60, Issue 10, Page 2294-2306, October 2020., 2020
Abstract Background To better understand donor behavior and ensure a safe and sufficient blood supply, various observational studies have examined barriers to blood donation. This study used Facebook and Twitter data to enhance existing research on donation barriers and associated emotions communicated on social media by both donors and non‐donors ...
Steven Ramondt, Melissa Zijlstra, Peter Kerkhof, Eva‐Maria Merz   +3 more
wiley   +1 more source

Y‐RNA subtype ratios in plasma extracellular vesicles are cell type‐ specific and are candidate biomarkers for inflammatory diseases

Journal of Extracellular Vesicles, Volume 9, Issue 1, September 2020., 2020
ABSTRACT Major efforts are made to characterize the presence of microRNA (miRNA) and messenger RNA in blood plasma to discover novel disease‐associated biomarkers. MiRNAs in plasma are associated to several types of macromolecular structures, including extracellular vesicles (EV), lipoprotein particles (LPP) and ribonucleoprotein particles (RNP).
Tom A.P. Driedonks, Sanne Mol, Sanne de Bruin, Anna‐Linda Peters, Xiaogang Zhang, Marthe F.S. Lindenbergh, Boukje M. Beuger, Anne‐Marieke D. van Stalborch, Thom Spaan, Esther C. de Jong, Erhard van der Vries, Coert Margadant, Robin van Bruggen, Alexander P.J. Vlaar, Tom Groot Kormelink, Esther N.M. Nolte‐‘T Hoen   +15 more
wiley   +1 more source

Cellular and Molecular Immunology Approaches for the Development of Immunotherapies against the New Coronavirus (SARS‐CoV‐2): Challenges to Near‐Future Breakthroughs

Journal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
The severe acute respiratory syndrome caused by the new coronavirus (SARS‐CoV‐2), termed COVID‐19, has been highlighted as the most important infectious disease of our time, without a vaccine and treatment available until this moment, with a big impact on health systems worldwide, and with high mortality rates associated with respiratory viral disease.
Juliana Gil Melgaço, Danielle Brito e Cunha, Tamiris Azamor, Andrea Marques Vieira da Silva, Luciana Neves Tubarão, Rafael Braga Gonçalves, Robson Q. Monteiro, Sotiris Missailidis, Patricia Cristina da Costa Neves, Ana Paula Dinis Ano Bom, Carlo Cavaliere   +10 more
wiley   +1 more source

Valor do Diâmetro do Átrio Esquerdo com Escore CHA2DS2-Vasc na Predição da Trombose Atrial Esquerda/Trombose de Apêndice Atrial Esquerdo na Fibrilação Atrial Não Valvar [PDF]

Arquivos Brasileiros de Cardiologia
Resumo Fundamentos A fibrilação atrial é a arritmia persistente mais comum e é o principal fator que leva ao tromboembolismo. Objetivo Investigar o valor do diâmetro do átrio esquerdo combinado com o escore CHA2DS2-VASc na predição da trombose atrial
Yu Zhang, Yi-Qiang Yuan
doaj   +3 more sources

Tromboembolismo venoso na mulher: novos desafios para uma velha doença [PDF]

Jornal Vascular Brasileiro, 2020
Resumo Nos países que controlaram as causas clássicas de óbito materno, como eclâmpsia e hemorragia, o tromboembolismo venoso (TEV) passou a ser a principal preocupação.
André Luiz Malavasi Longo de Oliveira, Adilson Ferraz Paschôa, Marcos Arêas Marques   +2 more
doaj   +3 more sources

Doença de Behçet com extensa trombose venosa Behçet disease with vast venous thrombosis

Revista Brasileira de Reumatologia, 2006
A doença de Behçet é uma entidade clínica rara que pode acometer o sistema vascular, levando à trombose de grandes vasos. Os autores descrevem um caso de trombose extensa, em um paciente jovem, como manifestação desta doença.Behçet disease is a rare ...
Varlei Antonio Serratto, Juliana Gomes Loyola Netto, Lysandra Yoshizumi, Eduardo Paiva   +3 more
doaj   +1 more source

Trombectomia em caso grave de trombose venosa iliofemoral afetando a veia femoral profunda pela técnica de punção e sessão única realizada pela veia jugular: relato de caso e descrição da técnica

Jornal Vascular Brasileiro, 2022
Resumo A trombectomia mecânica venosa ilíaca geralmente é realizada por acesso em veias localizadas nos membros inferiores, o que impossibilita o tratamento da veia femoral profunda, que, por sua vez, é uma importante via de influxo ao stent venoso ...
Fabio Henrique Rossi
doaj   +2 more sources

Desvendando a síndrome antifosfolípide catastrófica (síndrome de Asherson) Catastrophic antiphospholipid syndrome (Asherson's Syndrome) revealed

Revista Brasileira de Reumatologia, 2005
O quadro clínico de trombose generalizada de múltiplos órgãos acompanhada de insuficiência ou falência dos mesmos, em associação com anticorpos antifosfolípides, é chamado de "síndrome antifosfolípide catastrófica" (síndrome de Asherson).
Eduardo F. Borba, Eloísa Bonfá, Ronald A. Asherson   +2 more
doaj   +1 more source