Results 11 to 20 of about 6,299 (209)

Eltrombopag use in surgical procedures in inherited thrombocytopenia: expanding the role of thrombopoietin-receptor agonists [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Inherited thrombocytopenias (ITs) are a group of rare disorders characterized by low platelet counts and variable bleeding risk. Surgical procedures in these patients often require transient platelet elevation.
Miguel de Oliveira, Maria Coutinho, Eugénia Cruz, Sara Morais   +3 more
doaj   +2 more sources

Trombose dos Seios Intracranianos [PDF]

Anais da Faculdade de Medicina de Olinda, 2022
Introdução: A trombose do seio venoso cerebral é uma condição rara cujo diagnóstico pode ser realizado pela tomografia computadorizada, ressonância magnética ou por angiografia por cateterismo. Relato do caso: Paciente do sexo feminino, 27 anos, com quadro de cefaleia intensa holocraniana, pulsátil retro-ocular e turvação visual, além de crise ...
Joanna Pimentel de Vasconcelos, Marcos Antônio Barbosa da Silva, Rafael Jackes Péres, Isadora Silva de Lira, David Placido Lopes, Fernando Augusto Pacífico   +5 more
core   +4 more sources

Trombose, Hemorragia e Trombocitopenia Induzidas pelas Vacinas contra a COVID-19: Protocolo de Atuação [PDF]

Acta Médica Portuguesa, 2021
Após a generalização da vacinação contra a COVID-19, foram relatados efeitos adversos como trombose, hemorragia e trombocitopenia. Recentemente, após vacinação, foi reconhecido um síndrome raro e com mortalidade elevada, caraterizado por uma combinação ...
Sara Morais, Eugénia Cruz
doaj   +6 more sources

AGENESIA DE VEIA CAVA INFERIOR ASSOCIADA À TROMBOSE VENOSA PROFUNDA EM JOVENS [PDF]

Revista Uningá, 2018
A agenesia de veia cava inferior é uma anomalia congênita muito rara, que a poucos anos foi identificada como um importante fator de risco para o desenvolvimento e a recorrência de trombose venosa profunda de membros inferiores em pacientes jovens.
José de Paula Faria Neto, Rosana Lopes de Sousa Miranda   +1 more
doaj   +2 more sources

Detachment of Hexokinase II From Mitochondria Promotes Collateral Sensitivity in Multidrug Resistant Chronic Myeloid Leukemia Cells

Frontiers in Oncology, 2022
Chronic Myeloid Leukemia is a neoplastic disease characterized by the abnormal expansion of hematopoietic cells with compromised functions. Leukemic cells often display a multidrug resistance phenotype, enabling them to evade a number of structurally ...
Thaís Oliveira, Douglas Lemos, Louise Jean, Jéssica M. Kawashima, Vitória R. de Azevedo, Eduardo J. Salustiano, Vivian M. Rumjanek, Robson Q. Monteiro   +7 more
doaj   +1 more source

Inflammatory and Hemostatic Markers in COVID-19 Patients with Arterial Thrombosis Are Significantly Lower at Hospital Admission than in COVID-19 Patients without Thrombosis

Viruses, 2022
Patients with Coronavirus disease 2019 (COVID-19) are at increased risk of venous thromboembolism (VTE); however, data on arterial thromboembolism (ATE) is still limited.
Miguel de Oliveira, Francisco Cubal, Maria Coutinho, Mónica Pereira, Eugénia Cruz, Sara Morais   +5 more
doaj   +1 more source

MAIN BLOOD SERUM METABOLITES RESPONSIBLE FOR THE DISCRIMINATION OF HOSPITALIZED PATIENTS WITH MODERATE SYMPTOMS WITH OR WITHOUT COVID-19

Hematology, Transfusion and Cell Therapy, 2021
Introduction: The variation in human blood serum metabolites resulting from an infection can assist in understanding mechanisms of pathogen action and body response and improve diagnosis. Aim: To map serum signatures of hospitalized symptomatic patients,
LG Martins, SS Martins, ES Braga, D Stanisic, SAL Montalvão, LQ Silva, SC Huber, T Diaz, C Wroclawski, CC Filho, L Tasic, JM Annichino-Bizzacchi   +11 more
doaj   +1 more source

TROMBOSE VENOSA PORTAL EM TRANSPLANTAÇÃO HEPÁTICA – NOSSOS RESULTADOS E TÉCNICA CIRÚRGICA

Brazilian Journal of Transplantation, 2021
Introdução: Transplante de fígado ainda é um desafio cirúrgico, principalmente nos casos de trombose da veia porta. Enquanto alguns doentes em lista para transplante hepático são diagnosticados com essa condição no pré-operatório, outros são detetados ...
Nádia Silva, João Santos Coelho, Hugo Pinto Marques, Américo Martins   +3 more
doaj   +1 more source

A new case of platelet‐type von Willebrand disease supports the recent findings of gain‐of‐function GP1BA variants outside the C‐terminal disulphide loop enhances affinity for von Willebrand factor

British Journal of Haematology, Volume 203, Issue 4, Page 673-677, November 2023., 2023
Summary Platelet‐type von Willebrand disease (PT‐VWD) is a rare autosomal dominant bleeding disorder characterized by an increased ristocetin‐induced platelet aggregation (RIPA) and enhanced affinity of platelet glycoprotein Ibα (GPIbα) to von Willebrand factor (VWF).
Catarina Monteiro, Ana Gonçalves, Mónica Pereira, Catarina Lau, Sara Morais, Rosário Santos   +5 more
wiley   +1 more source

Off‐target effects of oral anticoagulants – vascular effects of vitamin K antagonist and non‐vitamin K antagonist oral anticoagulant dabigatran etexilate

Journal of Thrombosis and Haemostasis, Volume 19, Issue 5, Page 1348-1363, May 2021., 2021
Abstract Introduction Vitamin K antagonists (VKA) and non‐vitamin K oral antagonist anticoagulants (NOAC) are used in the clinic to reduce risk of thrombosis. However, they also exhibit vascular off‐target effects. The aim of this study is to compare VKA and NOAC on atherosclerosis progression and calcification in an experimental setup.
Rick H. van Gorp, Ingrid Dijkgraaf, Vanessa Bröker, Matthias Bauwens, Peter Leenders, Danyel Jennen, Marc R. Dweck, Jan Bucerius, Jacco J. Briedé, Joanne van Ryn, Vincent Brandenburg, Felix Mottaghy, Henri M. H. Spronk, Chris P. Reutelingsperger, Leon J. Schurgers   +14 more
wiley   +1 more source