Results 11 to 20 of about 32,593 (167)

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk. [PDF]

Br J Haematol
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Marín-Quílez A, Sánchez-Fuentes A, Zamora-Cánovas A, Gómez-González PL, Diaz-Ajenjo L, Benito R, Rodríguez-Alén A, Sevivas T, Murciano T, Murillo L, Butta NV, Revilla N, Campos R, Escribano P, Esteve J, Fernández-Mosteirin N, Ferrer-Marín F, Hernández L, Huerta-Aragonés J, León A, López-Duarte M, López E, Martín-Salces M, Nomdedeu M, Oña R, Peláez-Pleguezuelos I, Ramos F, Sebastián E, Serrano C, Sierra-Aisa C, Vidal-Laso R, González-Porras JR, Lozano ML, Bastida JM, Rivera J.   +34 more
europepmc   +2 more sources

Risk Profile of Patients with Spontaneous Cervical Artery Dissection

Annals of Neurology, Volume 94, Issue 3, Page 585-595, September 2023., 2023
Objective Epidemiological data to characterize the individual risk profile of patients with spontaneous cervical artery dissection (sCeAD) are rather inconsistent. Methods and Results In the setting of the Italian Project on Stroke in Young Adults Cervical Artery Dissection (IPSYS CeAD), we compared the characteristics of 1,468 patients with sCeAD ...
Elisabetta Del Zotto, Mario Grassi, Marialuisa Zedde, Andrea Zini, Anna Bersano, Carlo Gandolfo, Giorgio Silvestrelli, Claudio Baracchini, Paolo Cerrato, Corrado Lodigiani, Simona Marcheselli, Maurizio Paciaroni, Alessandra Spalloni, Manuel Cappellari, Massimo Del Sette, Anna Cavallini, Enrico Maria Lotti, Maria Luisa Delodovici, Mauro Gentile, Mauro Magoni, Marina Padroni, Cristiano Azzini, Maria Vittoria Calloni, Elisa Giorli, Massimiliano Braga, Paolo La Spina, Fabio Melis, Rossana Tassi, Valeria Terruso, Rocco Salvatore Calabrò, Valeria Piras, Alessia Giossi, Sandro Sanguigni, Carla Zanferrari, Marina Mannino, Irene Colombo, Carlo Dallocchio, Patrizia Nencini, Valeria Bignamini, Alessandro Adami, Rita Bella, Rosario Pascarella, Zafer Keser, Alessandro Pezzini, the Italian Project on Stroke in Young Adults—Cervical Artery Dissection, (IPSYS CeAD) Research Group   +45 more
wiley   +1 more source

Dilemmas on emicizumab in children with haemophilia A: A survey of strategies from PedNet centres

Haemophilia, Volume 29, Issue 5, Page 1291-1298, September 2023., 2023
Abstract Introduction Haemophilia A care has changed with the introduction of emicizumab. Experience on the youngest children is still scarce and clinical practice varies between haemophilia treatment centres. Aim We aimed to assess the current clinical practice on emicizumab prophylaxis within PedNet, a collaborative research platform for ...
Susanna Ranta, Jayashree Motwani, Jan Blatny, Martina Bührlen, Manuel Carcao, Hervé Chambost, Carmen Escuriola, Kathelijn Fischer, Mutlu Kartal‐Kaess, Marloes de Kovel, Gili Kenet, Christoph Male, Beatrice Nolan, Roseline d'Oiron, Martin Olivieri, Ester Zapotocka, Nadine G. Andersson, Christoph Königs   +17 more
wiley   +1 more source

Deep sequencing of circulating miRNAs and target mRNAs level in deep venous thrombosis patients

IET Systems Biology, Volume 17, Issue 4, Page 212-227, August 2023., 2023
Eight differentially expressed miRNAs including hsa‐miR‐150‐5p, hsa‐miR‐326, hsa‐miR‐144‐3p, hsa‐miR‐199a‐5p, hsa‐miR‐199b‐5p, hsa‐miR‐125a‐5p, hsa‐let‐7e‐5p and hsa‐miR‐381‐3p and their target mRNAs (PRKCA, SP1, TP53, SLC27A4, PDE1B, EPHB3, IRS1, HIF1A, MTUS1 and ZNF652) were found associated with deep venous thrombosis for the first time ...
Qingxian Wang, Yunhe Chang, Xuqing Yang, Ziwang Han   +3 more
wiley   +1 more source

Effect of external dead space removal on CO2 homeostasis in mechanically ventilated adult Covid‐19 patients

Acta Anaesthesiologica Scandinavica, Volume 67, Issue 7, Page 936-942, August 2023., 2023
Abstract Background Patients with Covid‐19 respiratory failure present with hypoxemia, often in combination with hypercapnia. In this prospective, observational study we examined the effect of removing external dead space (DS) on CO2‐homeostasis in mechanically ventilated Covid‐19 patients.
Tomas Öhman, Francesca Campoccia Jalde, Magnus Fredby, Håkan Björne, Jacob Karlsson   +4 more
wiley   +1 more source

PB2652: EVALUATION OF 6 CASES WITH FXIII DEFICIENCY: SINGLE CENTRE EXPERIENCE

, 2023
HemaSphere, Volume 7, Issue S3, August 2023.
Fahri Sahin, Denis Bozer, Zuhal Demirci, Guray Saydam   +3 more
wiley   +1 more source

Anticuerpos anti-beta2-glicoproteina I:Prevalencia en pacientes portadores de insuficiencia real cronica en hemodialisis [PDF]

, 1999
50 p.Los Anticuerpos Anti-Fosfolípido-Proteína (aFL-P) se encuentran en el Síndrome Antifosfolípido Primario (SAF), enfermedades autoinmunes y otras afecciones.
Hernandez Liberona, Alex, Tapia Sanhueza, Jaime (Prof. Guia)   +1 more
core  

Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema

Clinical &Experimental Ophthalmology, Volume 53, Issue 7, Page 825-833, September/October 2025.
ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa, Rodrigo S. Pegado, Fernanda N. Susanna, Kenzo Hokazono, Mário Luiz R. Monteiro, Leonardo Provetti Cunha   +5 more
wiley   +1 more source

Impact of Family History of Haemophilia on Diagnosis, Management and Outcomes in Severe Haemophilia

Haemophilia, Volume 31, Issue 4, Page 679-686, July 2025.
ABSTRACT Introduction Patients with severe haemophilia A (HA) with no family history of haemophilia will be diagnosed upon their first bleeding event. Methods Herein, we studied the effects of lack of family history in HA and the subsequent delay of diagnosis on bleeding pattern and early treatment, as well as on the risk of inhibitor development.
Ana Mendoza, Isabel Rivas, Olga Benítez Hidalgo, Ana Rosa Cid, Martin Olivieri, Susanna Ranta, Veerle Labarque, Nadine G. Andersson, Marloes de Kovel, María Teresa Álvarez‐Román   +9 more
wiley   +1 more source

Trombosis venosa cerebral

Revista Cubana de Medicina, 2020
RESUMEN En la actualidad la trombosis venosa cerebral (TVC) se considera un reto diagnóstico y terapéutico, debido a la alta variabilidad de presentación y a la falta de un consenso terapéutico claro. Representa 0,5 % de los ictus y afecta con mayor frecuencia a sujetos jóvenes con factores de riesgo congénitos o adquiridos.
José Luis Miranda Hernández, Leda Fernández Cué   +1 more
openaire   +1 more source