Results 71 to 80 of about 3,279,066 (304)

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai   +9 more
wiley   +1 more source

The current state and dynamics of the flora of several small lakes of the Yaroslavl Region, Russia

open access: yesТрансформация экосистем, 2020
The phytoplankton and vascular aquatic plants have been studied in small lakes Vashutinskoe, Chashnitskoe, Ryumniki, and Zaozer’e, located in the southern part of the Yaroslavl Region, Russia.
Evgeny A. Belyakov   +2 more
doaj   +1 more source

Assessing trophic status of Suoi Hai Reservoir using Carlson’s Trophic State Index

open access: yes, 2021
The water quality of Suoi Hai reservoir, the largest reservoir in Hanoi city, is being threatened by human activities of the surrounding area, as reported by the press.
Vinh Pham Quang   +7 more
core   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

open access: yesAdvanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun   +13 more
wiley   +1 more source

Trophic model-generated indicators of the southern Benguela ecosystem for communicating with fisheries managers [PDF]

open access: yes, 2010
Includes abstract.Includes bibliographical references (leaves 112-121).An Ecosystem Approach to Fisheries (EAF) is the new management paradigm considered for ecosystems worldwide.
Osman, Wisaal
core   +1 more source

Studi Evaluasi Kualitas Dan Status Trofik Air Waduk Selorejo Akibat Erupsi Gunung Kelud Untuk Budidaya Perikanan

open access: yesJurnal Teknik Pengairan, 2015
Selorejo dam in Malang regency has been used as a water storage and for freshwater fishery. On February 13 th 2014, Mount Kelud was erupted and produced volcanic ash which fell into the reservoir and caused an imbalanced water quality.
Rini Wahyu Sayekti   +6 more
doaj  

Effects of Climate Events on the Trophic Status of an Amazonian Estuary

open access: yesLimnological Review
In recent years, climate events such as Drought, El Niño, and La Niña have become increasingly frequent and more intense. Oceanographic monitoring was used to collect hydrological data in the middle and lower sectors of the Caeté estuary in different years.
Marcela Cunha Monteiro   +2 more
openaire   +2 more sources

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Driving forces shaping phytoplankton assemblages in two subtropical plateau lakes with contrasting trophic status

open access: yes, 2007
1. We studied driving forces shaping phytoplankton assemblages in two subtropical plateau lakes with contrasting trophic status, the oligotrophic deep Lake Fuxian and the eutrophic shallow Lake Xingyun. 2.
Xie, P, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China   +5 more
core   +1 more source

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