Results 121 to 130 of about 51,241 (234)

Fluid percussion trauma to the placental trophoblast triggers multifaceted injury mechanisms, including mitochondrial stress response, immune dysregulation, cytoskeletal, endothelial, and angiogenic signaling cascades. [PDF]

Front Cell Dev Biol
Paidas MJ, West EM, Speciale AR, Patel UC, Ramamoorthy R, Kumar S, Patrizio R, Belkin EM, Attia C, Shaikh A, Kandasamy G, Ahmad N, Porter E, Ahmad A, Jayakumar AR.   +14 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Autophagy in the Regulation of Placental Development: From Trophoblast Differentiation to Metabolic Stress Adaptation. [PDF]

Cells
Lee C, Leung HKM, Guo Y, Wong SCS, Zhang R, Chan LT, Dong Y, Zhang Q, Cheung KW, Chiu PCN, Lee CL.   +10 more
europepmc   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

Cuproptosis: a novel mechanism linking placental metabolic stress to trophoblast injury in preeclampsia. [PDF]

Front Endocrinol (Lausanne)
Liu L, Xing B, Zhang Y.
europepmc   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

Trophoblast Enrichment by Maternal Immune-Cell Depletion Using CD45 and CD56 Surface Markers in Trophoblast Retrieval and Isolation from the Cervix (TRIC). [PDF]

Diagnostics (Basel)
Jang H, Son HJ, Go M, Kim JC, Park JE, Kim H, Park HJ, Kim SH, Shim SS, Han YJ, Lee YJ, Shim SH, Cha DH.   +12 more
europepmc   +1 more source

Trophoblast [PDF]

, 2020
openaire   +1 more source

L-(+)-Ergothioneine ameliorates preeclampsia-associated vascular endothelial dysfunction by modulating the Nrf2-PPARγ-sFlt-1 axis. [PDF]

PLoS One
Gong J, Liu Y, Meng Q, Wu J, Chen F, Xu Y, Li Y, Luo Q.   +7 more
europepmc   +1 more source