Results 111 to 120 of about 60,792 (295)

The pivotal role of insulin-like growth factors in pregnancy success.

, 2007
Appropriate placental development in early gestation is essential for subsequent placental function and hence optimal fetal growth and pregnancy outcome.
Sferruzzi-Perri, Amanda Nancy
core  

Placental basal plate with attached myofibers and adverse pregnancy outcomes: A systematic scoping review

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The presence of basal plate myometrial fibers was associated with higher rates of placenta‐related pregnancy disorders and abnormal placental attachment in subsequent pregnancies, but heterogeneity in the data was found due to variable inclusion criteria, sampling methods, and reported outcomes.
Eric Jauniaux, Helena C. Bartels, Paul Downey, Francesco D'Antonio   +3 more
wiley   +1 more source

Chlamydia trachomatis Infection of Human Trophoblast Alters Estrogen and Progesterone Biosynthesis: an insight into role of infection in pregnancy sequelae

International Journal of Medical Sciences, 2007
The trophoblast cells are in direct contact with endometrial tissues throughout gestation, playing important early roles in implantation and placentation.
Anthony A. Azenabor, Patrick Kennedy, Salvatore Balistreri
doaj  

Transient inhibition of MEK/ERK and WNT pathways enhances direct differentiation of primed hPSCs into functional trophoblast stem cells

Cell Regeneration
The placenta plays a pivotal role in human pregnancy, yet research into placental development has been hindered by limited access to early-stage embryos and ethical constraints.
Qifan Jiang, Ping Liu, Chunlin Chen
doaj   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Regulation of Trophoblast Invasion-A Workshop Report.

, 2007
Trophoblast invasion during placental development helps to establish efficient physiological exchange between maternal and fetal circulatory systems. Trophoblast stem cells differentiate into multiple subtypes, including some that are highly invasive ...
Harris, LK; id_orcid, Knöfler, M, Armant, DR., Lash, GE, Simmons, DG   +4 more
core   +2 more sources

Regulation of trophoblast invasion - A workshop report

, 2008
Trophoblast invasion during placental development helps to establish efficient physiological exchange between maternal and fetal circulatory systems. Trophoblast stem cells differentiate into multiple subtypes, including some that are highly invasive ...
Knöfler, M., Harris, Lynda K., Simmons, David G., M. Knöfler, Lash, Gendie E., D.G. Simmons, L.K. Harris, Harris, L. K., Knöfler, Martin, Armant, D. R., Lash, G. E., Armant, David Randall, Simmons, D. G., D.R. Armant, G.E. Lash   +14 more
core   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Materno-fetal nutrient transfer across primary human trophoblast layer.

, 2014
MATERNO-FETAL NUTRIENT TRANSFER ACROSS PRIMARY HUMAN TROPHOBLAST MONOLAYER\ud Objectives: Polarized trophoblasts represent the transport and metabolic barrier between the maternal and fetal circulation.
Baumann, Marc Ulrich, Huang, Xiao, Ontsouka, Edgar, Albrecht, Christiane, Lüthi, Michael, Surbek, Daniel   +5 more
core  

Human trophoblast interferons

, 1993
The human placental trophoblasts which constitute the first fetal cells and form the major cell layer of the feto-maternal interface are potent producers of interferons (IFNs).
Zdravkovic, Milan, Ebbesen, Peter, Aboagye-Mathiesen, George, Toth, Ferenc D., Hager, Henrik, Villadsen, Jan A., Zachar, Vladimir; id_orcid, Petersen, Peter M.   +7 more
core   +1 more source