Results 91 to 100 of about 49,121 (248)

Uterus‐preserving surgery for placenta accreta spectrum: An expert, illustrated review of techniques and its outcomes

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Uterus‐preserving strategies for PAS include myometrial resection and leaving placenta in situ, differing in surgical principles, complications, and follow‐up. Myometrial resection offers definitive treatment with lower rates of delayed morbidity, while leaving the placenta in situ minimizes surgical risk but is associated with prolonged follow‐up ...
Pedro Viana Pinto, Albaro José Nieto‐Calvache, Rafael José Vieira, Abdalla Mousa, Hooman Soleymani majd, Rozi Aditya Aryananda, José Miguel Palacios‐Jaraquemada   +6 more
wiley   +1 more source

Clinicopathological phenotypes of singleton stillbirth: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Clinical information, description of placenta, and umbilical cord were reviewed, and microscopic slides re‐evaluated according to the Amsterdam Consensus. Stillbirths with maternal vascular malperfusion often had signs of high‐risk pregnancy, unlike stillbirths with villitis of unknown etiology, fetal vascular malperfusion, and umbilical cord at risk ...
Ragnheidur I. Bjarnadottir, Thora S. Steffensen, Alexander K. Smarason, Karin Pettersson, Nikos Papadogiannakis, Johanna Gunnarsdottir   +5 more
wiley   +1 more source

Mechanism of miR-20b-5p targeting HIF-1α in regulating trophoblast function in recurrent spontaneous abortion

European Journal of Medical Research
Objective Recurrent spontaneous abortion (RSA) is a major pregnancy complication with unclear pathogenesis. This study aims to investigate the role of miR-20b-5p and its downstream target HIF-1α in trophoblast function and RSA pathogenesis.
Yihong Guo, Qiaoxian Wu, Lujing Chen, Yanyu Lai, Aizhen Fu   +4 more
doaj   +1 more source

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm, Lotte Krog Eriksen, Kathrine Dyhr Lycke, Ninna Lund Larsen, Iben Sundtoft, Tina Hovgaard Randrup, Anne Hammer   +6 more
wiley   +1 more source

Prophylactic ureteral stent placement for the prevention of urinary tract injuries in women with placenta accreta spectrum undergoing peripartum cesarean hysterectomy: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Prophylactic ureteral stent placement was associated with a reduced risk of urinary tract injury in women with placenta accreta spectrum undergoing peripartum cesarean hysterectomy, independent of prior cesarean number. Abstract Introduction This retrospective cohort study investigated whether preoperative bilateral ureteral stent placement reduces ...
Hasan Berkan Sayal, And Yavuz, Merve Turk, Busra Tsakir, Erzat Toprak, Zeynep Ozturk Inal   +5 more
wiley   +1 more source

Longitudinal circulating tumour DNA identifies patients at high risk of upstaging and recurrence in non‐muscle‐invasive bladder cancer

BJU International, EarlyView.
Objectives To evaluate whether longitudinal tumour‐informed circulating tumour DNA (ctDNA) testing identifies patients at increased risk of upstaging and recurrence in high‐risk non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods A cohort of 52 patients with high‐risk NMIBC underwent serial plasma ctDNA testing using a personalised tumour ...
Can Aydogdu, Betty Wang, Sean Thomas McSweeney, Gabriela Diaz, Taeris Guzman, Sahab Ram Dewala, Rakesh Arya, Mikayla Baer, Amanda Nizam, Christopher Wee, Shalini Moningi, Alberto Pieretti, Christopher J. Weight, Rebecca Campbell, Mohit Sindhani, Jihad Kaouk, Robert Abouassaly, Laura Bukavina   +17 more
wiley   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Gestational trophoblastic disease [PDF]

JAAPA, 2017
J Kenneth, Schoolmeester, Lori A, Erickson   +1 more
openaire   +4 more sources