Results 231 to 240 of about 87,349 (342)

Aspirin Discontinuation at 24–28 Weeks and Placental Biomarker Trajectories: Post Hoc Analysis of a Randomised Trial

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 3, Page 432-441, February 2026.
ABSTRACT Objective To compare the trajectories of placental biomarkers throughout pregnancy after aspirin discontinuation at 24–28 weeks with those of a cohort treated until 36 weeks of gestation. Design A longitudinal secondary analysis of the StopPRE trial, using repeated measures of soluble fms‐like tyrosine kinase‐1 (sFlt‐1), placental growth ...
Erika Bonacina   +29 more
wiley   +1 more source

Melatonin mitigates Autophagy: Unlocking Conditional Resilience in Sheep Trophoblast Cells Exposed to a Hypoxic Environment. [PDF]

open access: yesReprod Fertil
Viola I   +7 more
europepmc   +1 more source

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen   +18 more
wiley   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

open access: yesAndrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell   +12 more
wiley   +1 more source

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