Results 301 to 310 of about 109,495 (390)

Dynamics of Cell Fate Decisions during Chemically Induced Multi‐Lineage Trans‐Differentiation at Single‐Cell Level

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A critical aspect of chromosomal remodeling in small molecule‐induced multilineage trans‐differentiation(iMT) is elucidated. A dynamic atlas spanning over 35 days profiles terminal trans‐differentiated cells, which reverted to a more youthful state. This study reveals parallels between iMT and other cell fate determination processes, emphasizing an ...
Weigao E, Lijiang Fei, Jingjing Wang, Xinru Wang, Renying Wang, Xueyi Wang, Peijing Zhang, Jianhui Chen, Junqing Wu, Mengmeng Jiang, Daosheng Huang, Danmei Jia, Guoji Guo, Xiaoping Han   +13 more
wiley   +1 more source

Extracellular matrix and pregnancy: functions and opportunities caught in the net. [PDF]

Reprod Biol Endocrinol
Rossi F, Luppi S, Fejza A, Giolo E, Ricci G, Andreuzzi E.   +5 more
europepmc   +1 more source

The role of trophoblast in the physiological change in decidual spiral arteries

, 1999
Elisa Kam, Lucy Gardner, Y.W. Loke, Ashley King   +3 more
openalex   +1 more source

DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells

Advanced Science, Volume 12, Issue 17, May 8, 2025.
This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang, Ying Yang, Linlin Xu, Chaoju Hao, Jiaxiang Chen   +4 more
wiley   +1 more source

MicroRNAs in Preeclampsia: Bridging Diagnosis and Treatment. [PDF]

J Clin Med
Gerede A, Stavros S, Danavasi M, Potiris A, Moustakli E, Machairiotis N, Zikopoulos A, Nikolettos K, Drakakis P, Nikolettos N, Eleftheriades M, Domali E.   +11 more
europepmc   +1 more source

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, Volume 12, Issue 17, May 8, 2025.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

Cell Signaling Pathways Involved During Invasion and Syncytialization of Trophoblast Cells

American Journal of Reproductive Immunology, 2016
S. Gupta, S. S. Malhotra, Ankita Malik, S. Verma, Piyush Chaudhary   +4 more
semanticscholar   +1 more source

tRF-5028c disrupts trophoblast function in recurrent spontaneous abortion by inhibiting CRKL-mediated Rap1 signaling pathway. [PDF]

Cell Mol Biol Lett
Huang J, Wang J, Wang S, Xiong X, Jiang R, Xiong C, Wang L, Huang L, Zhao Y, Fang Z, Ai X, Lin J.   +11 more
europepmc   +1 more source

Plac1+ Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Meng et al. screen genes in the CTAs family and find Plac1 is specifically expressed in head and neck squamous cell carcinoma (HNSCC) cells. They reveal that Plac1 expression promotes HNSCC progression directly by activating PI3K/AKT signaling pathway.
Xiaoyan Meng, Zhonglong Liu, Lu Zhao, Ran Li, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +8 more
wiley   +1 more source

Upregulation of Autophagy During the Differentiation of Primary Human Term Cytotrophoblast Cells into Syncytial Cells: Ultrastructural Analysis. [PDF]

Int J Mol Sci
Tozawa S, Takahashi H, Noguchi S, Takizawa T, Sakurai T, Ohkuchi A, Fujiwara H, Takizawa T.   +7 more
europepmc   +1 more source