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Clinics in Obstetrics and Gynaecology, 1982
Molar pregnancy should always be considered as a possible diagnosis in any pregnancy that does not conform to the normal. The practice of subjecting all pregnant women to ultrasound B-scan at their first visit in some centres is commendable, but unfortunately not possible in the areas of high incidence, owing to lack of facilities.
A. Ilancheran, Ratnam Ss
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Molar pregnancy should always be considered as a possible diagnosis in any pregnancy that does not conform to the normal. The practice of subjecting all pregnant women to ultrasound B-scan at their first visit in some centres is commendable, but unfortunately not possible in the areas of high incidence, owing to lack of facilities.
A. Ilancheran, Ratnam Ss
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Gestational trophoblastic diseases [PDF]
International Journal of Gynecology & Obstetrics, 2003 In 1991, FIGO added non-surgical-pathologic prognostic risk factors to the classic anatomical staging system. These include urinary hCG levels >100000mIU/ml and/or serum b-hCG >40000mIU/ml and the duration of an antecedent pregnancy being >6 months. Since gestational trophoblastic diseases (GTD) have a very high cure rate in virtually all patients, the
Ngan, H. Y +7 more
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Placental site trophoblastic tumour and epithelioid trophoblastic tumour
Best Practice & Research Clinical Obstetrics & Gynaecology, 2021Placental site trophoblastic tumour (PSTT) and epithelioid trophoblastic tumour (ETT) are the rarest subtypes of gestational trophoblastic disease (GTD). Their diagnosis is complicated and lacks specific and sensitive tumour markers. They are slow-growing tumours and can occur months to years after any type of antecedent pregnancy.
Barry W. Hancock, John Tidy
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Antibody reactivity against trophoblast and trophoblast products
Journal of Reproductive Immunology, 1985Sensitive immunoassays have been applied to WHO reference bank sera from fertile and infertile women in order to assess any naturally occurring antibody reactive with isolated human placental trophoblast membranes or two separate trophoblast protein products (hCG and SP1).
Vernon C. Stevens +3 more
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Gestational Trophoblastic Disease
Obstetrics & Gynecology, 2006This review summarizes the primary management of molar pregnancies, surveillance after evacuation, and the evaluation and management of malignant gestational trophoblastic neoplasia (GTN). Most women with gestational trophoblastic disease can be successfully managed with preservation of their normal reproductive function.
Chan, KKL, Ngan, HYS, Tam, KF
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Human Fertility, 2004
Trophoblast invasion can be seen as a tightly regulated battle between the competing interests of the survival of the fetus and those of the mother. Successful pregnancy is dependent on the trophoblast invading the mother, attaching the pregnancy to the uterus and securing an adequate supply of oxygen and nutrient to the fetus.
Sheba Anin, Anin +2 more
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Trophoblast invasion can be seen as a tightly regulated battle between the competing interests of the survival of the fetus and those of the mother. Successful pregnancy is dependent on the trophoblast invading the mother, attaching the pregnancy to the uterus and securing an adequate supply of oxygen and nutrient to the fetus.
Sheba Anin, Anin +2 more
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2011
The villous trophoblast of the human placenta is the epithelial cover of the fetal chorionic villi floating in maternal blood. This epithelial cover is organized in two distinct layers, the multinucleated syncytiotrophoblast directly facing maternal blood and a second layer of mononucleated cytotrophoblasts.
Berthold, Huppertz, Martin, Gauster
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The villous trophoblast of the human placenta is the epithelial cover of the fetal chorionic villi floating in maternal blood. This epithelial cover is organized in two distinct layers, the multinucleated syncytiotrophoblast directly facing maternal blood and a second layer of mononucleated cytotrophoblasts.
Berthold, Huppertz, Martin, Gauster
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Annals of the New York Academy of Sciences, 1959
Literature on the biology of the trophoblast is reviewed. In Part 1 various hypotheses of the invasive mechanism of the trophoblast are criticized. In Part 2 an hypothesis to explain the invasion of abembryonic rabbit trophoblast by chemical and physical mechanisms is developed and applied.
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Literature on the biology of the trophoblast is reviewed. In Part 1 various hypotheses of the invasive mechanism of the trophoblast are criticized. In Part 2 an hypothesis to explain the invasion of abembryonic rabbit trophoblast by chemical and physical mechanisms is developed and applied.
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