Results 91 to 100 of about 8,177 (250)

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source

Comparison of ?-HCG Regression Curve in Molar Pregnancy and Gestational Trophoblastic Neoplasms

پزشکی بالینی ابن سینا, 2011
Introduction & Objective: All cases of gestational trophoblastic tumors are curable if exact diagnosis and early treatment is done. The serum level of βHCG is a sensitive marker of the disease.
Fatemeh Homaee, Maliheh Hassanzadeh, Zohreh Yousefi, Monavar Afzalaghaiee, Ali Yousefi   +4 more
doaj  

Analysis of histological frequency and pediatric cancer in Rondônia, Western Amazonia (Brazil) [PDF]

, 2018
Objective:Describe the histological and cancer frequency in children and adolescents attended at the Hospital de Base Dr. Ary Pinheiro and the Hospital de Barretos / Rondônia, Western Amazonia, in the years 2014 and 2015.
Aguiar, R. R. (Rodrigo), Almeida, F. M. (Fabrício), Paraguassú-Chaves, C. A. (Carlos), Romanholo, R. A. (Rafael), Souza, L. P. (Laurindo)   +4 more
core  

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

Clinics
Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells.
Lawrence H. Lin, Lisandra S. Bernardes, Eliane A. Hase, Koji Fushida, Rossana P.V. Francisco   +4 more
doaj   +1 more source

Enfortumab vedotin plus pembrolizumab in treatment‐naïve metastatic urothelial carcinoma patients: An Austrian real‐world analysis

International Journal of Cancer, Volume 158, Issue 6, Page 1654-1665, 15 March 2026.
What's new? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke, Karl Mayrhofer, Johanna Krauter, Johannes Franke, Dominic Vais, Maximillian Pallauf, David Kiesl, Ferdinand Luger, Jacob Pfuner, Angelika Terbuch, Thomas Bauernhofer, Jasmin Spielgelberg, Andreas Banner, Stefan Aufderklamm, Clemens Wiesinger, Susanne Schnabel, Simon Peter Gampenrieder, Josef Mühlmann, Sonia Vallet, Sabine Weibrecht, Franz Stoiber, Haleh Andalibi, Harun Fajkovic, Hossein Taghizadeh, Jan Miechowiecki, Roman Taedcke, Daniel Heintel, Shahrokh F. Shariat, Martin Pichler, Wolfgang Hilbe, Renate Pichler   +30 more
wiley   +1 more source

Homonymous Quadrantanopsia as the First Manifestation of Cerebral Metastasis of Invasive Mole: a case report

Journal of Medical Case Reports, 2012
Introduction Homonymous quadrantanopsia results from retrochiasmal lesions in the visual pathway. Invasive mole is a benign tumor that arises from myometrial invasion of a hydatidiform mole via direct extension through tissue or venous channels. Cerebral
Song De-Lu, Zhong Yong, Feng Feng, Li Yuan, Li Meng-Hui   +4 more
doaj   +1 more source

Circulating survivin levels in healthy and asthmatic pregnancy. [PDF]

, 2014
BACKGROUND: Asthma is one of the most common conditions which complicate pregnancy. Pro- and anti-apoptotic mechanisms can be modulated by asthma accompanying pregnancy.
Bikov András, Bohács Anikó, Böcskei Renáta, Eszes Noémi, Horváth Ildikó, Losonczy György, Rigó János, Tamási Lilla   +7 more
core   +1 more source

Spatial heterogeneity of antibody–drug conjugate targets in pancreatic ductal adenocarcinoma

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, with limited therapeutic options, few patients showing targetable molecular changes. New therapeutic strategies are necessary. Antibody–drug conjugates (ADCs) have emerged as alternative therapeutic strategies across various cancer types. Herein, we analyze the expression and spatial
Deema Sabtan, Marie‐Lisa Eich, Florian Loch, Julen Karl Pérez Zuschneid, Markus Möbs, Judith Böhme, Frederick Klauschen, David Horst, Mihnea P Dragomir, Gabriel Dernbach, Simon Schallenberg   +10 more
wiley   +1 more source

MR appearance of placental site gestational trophoblastic neoplasm

Clinical Imaging, 1996
The magnetic resonance imaging (MRI) findings of a patient with placental site trophoblastic tumor are presented. In this patient, a small focal mass distorting the junctional zone and invading the myometrium was identified. Due to the aggressive nature of this neoplasm and the difficulty in detecting it clinically, MRI may represent a useful tool in ...
N A, Beauchamp, J E, Kuhlman
openaire   +2 more sources