Results 91 to 100 of about 319,242 (298)
Hemophilia A: An Ideal Disease for Prenatal Therapy
Prenatal Diagnosis, EarlyView.ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo +5 more
wiley +1 more source
Gestational Trophoblastic Neoplasm cM1 TNM Finding v8 [PDF]
, 2020 National Cancer Institute
openalex +1 more source
CDKN1C/p57kip2 Is a Candidate Tumor Suppressor Gene in Human Breast Cancer [PDF]
, 2008 BACKGROUND. CDKN1C (also known as p57KIP2) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family members (CDKN1A/p21CIP1 and B/p27KIP1) have been implicated in breast cancer, but information about ...
de las Morenas, Antonio +8 more
core +3 more sources
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen +5 more
wiley +1 more source
Cancer Medicine, 2018 The human CGB5 gene encodes chorionic gonadotropin (hCG)β 5, which is aberrantly expressed in trophoblastic neoplasm and in some non‐trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth.
Yuxin Yang +4 more
doaj +1 more source
Gestational Trophoblastic Neoplasm pTX TNM Finding v8 [PDF]
, 2020 National Cancer Institute
openalex +1 more source
Keratoacanthoma-like nodules as first manifestation of metastatic epithelioid trophoblastic tumor [PDF]
, 2019 Cutaneous metastases are rarely the initial manifestation of a previously undiagnosed malignancy and keratoacanthoma-like lesions are a notoriously unusual presentation pattern of cutaneous dissemination of a primary tumor.
Cardoso, JC +6 more
core
Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents
Cell Proliferation, EarlyView.Our study (1) represented a first systematic analysis of species‐specific adaptation in the DNA binding pattern of transcription factor; (2) represented a first study of cis‐regulation between two reproductively isolated species by using a novel allodiploid system; (3) demonstrated a higher conservation of transcriptional output than that of DNA ...
Weizheng Liang +13 more
wiley +1 more source
Clinical management of ovarian small-cell carcinoma of the hypercalcemic type: A proposal for conservative surge [PDF]
, 2009 Ovarian small-cell carcinoma of the hypercalcemic type is a rare and highly malignant tumor. In two thirds of the patients, the tumor is associated with asymptomatic paraneoplastic hypercalcemia.
Burg, M. (Mirjam) van der +5 more
core +1 more source