Human Trophoblast Neoplasms: Proceedings of the World Congress on Trophoblast Neoplasms, Nairobi, 1982. Advances in Experimental Medicine and Biology [PDF]
Human Trophoblast Neoplasms: Proceedings of the World Congress on Trophoblast Neoplasms, Nairobi, 1982.
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Epidermal growth factor receptor is a marker for syncytiotrophoblastic cells in testicular germ cell tumors [PDF]
The epidermal growth factor receptor (EGFR) has been implicated in the pathogenesis, therapy and prognosis of various tumor types. The aim of this study was to investigate EGFR expression in a large series of testicular germ cell tumors (TGCTs).
Hechelhammer, Lukas+4 more
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In Vivo Reprogramming Highlights Epigenetic Regulation That Shapes Cancer Hallmarks
In this review, the authors first introduce genetic aberrations that cause cancer development. Then, they illustrate the impact of epigenetic abnormalities in cancer, especially with reference to studies that use in vivo reprogramming technologies. Finally, the authors discuss the importance of histological evaluations of tumor tissue to understand non‐
Yosuke Yamada+2 more
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Investigating Aging‐Related Endometrial Dysfunction Using Endometrial Organoids
Age‐associated fibrosis, imbalanced inflammatory homeostasis including Th1 bias in secretory phase, cellular senescence and decline of receptivity exist in human endometrium of advanced age. Overactivation of PI3K‐AKT‐FOXO1 signalling pathway could give rise to those characteristics above.
Minghui Lu+9 more
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MR appearance of placental site gestational trophoblastic neoplasm
The magnetic resonance imaging (MRI) findings of a patient with placental site trophoblastic tumor are presented. In this patient, a small focal mass distorting the junctional zone and invading the myometrium was identified. Due to the aggressive nature of this neoplasm and the difficulty in detecting it clinically, MRI may represent a useful tool in ...
Janet E. Kuhlman, Norman A. Beauchamp
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Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti‐apoptotic proteins.
Yu Chen+8 more
wiley +1 more source
A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm [PDF]
Uterine leiomyosarcoma (ULMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine ULMS
Akiko Horiuchi+5 more
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Organoids in Haematologic Research: Advances and Future Directions
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang+4 more
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Illustration of the preparation of tFNAs‐DJ‐1 saRNAs complex and its inhibitory effects on ferroptosis in R28 and retina. ABSTRACT Retinal ischaemia/reperfusion injury (RI/RI) is the primary pathophysiological mechanism underlying retinal ischaemic diseases, potentially resulting in significant and irreversible visual impairment.
Xianggui Zhang+10 more
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Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L.+4 more
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