Results 11 to 20 of about 3,524 (151)

Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report

Annals of Clinical and Translational Neurology
HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who ...
Jiahui Zeng, Wotu Tian, Jingran Yang, Yanping Yang, Li Cao, Xinghua Luan   +5 more
doaj   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. [PDF]

J Med Virol
ABSTRACT Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurodegenerative disease affecting motor and sensory functions. While alterations in cerebrospinal fluid (CSF) have been used to identify disease biomarkers, the effects of such modified CSF on CNS cells remain unexplored.
Gomes YCP, Bongers A, Jeannin P, Vicente ACP, Gessain A, Afonso PV, Espindola OM.   +6 more
europepmc   +2 more sources

Magnetic resonance imaging for Human T-cell lymphotropic virus type 1 (HTLV1-) associated myelopathy/tropical spastic paraparesis patients: a systematic review [PDF]

Reviews in Clinical Medicine, 2015
Introduction: Human T-cell lymphotropic virus type 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis is a chronic progressive neurologic disease which might be associated by brain and spinal cord atrophy and lesions.
Fariba Zemorshidi, Reza Boostani, Mohammad Mehdi Etemadi   +2 more
doaj   +3 more sources

Intravesical injection of onabotulinumtoxinA in neurogenic overactive bladder patients with human T‐cell leukemia virus type 1‐associated myelopathy: A single‐institution case series

IJU Case Reports, 2021
Introduction Neurogenic overactive bladder is a main feature of human T‐cell leukemia virus type 1‐associated myelopathy/tropical spastic paraparesis. We successfully performed intravesical onabotulinumtoxinA therapy for refractory neurogenic overactive ...
Tomohiro Matsuo, Tatsufumi Nakamura, Katsuya Sato, Yasuyoshi Miyata, Hideki Sakai   +4 more
doaj   +1 more source

Morbidity and Mortality Among People Living With HTLV-1: A 30-Year Retrospective Analysis in a Brazilian Cohort. [PDF]

J Med Virol
ABSTRACT HTLV‐1 infection is a chronic condition associated with the development of malignancies, inflammatory, and neurological disorders. In this study, the causes of hospitalization and mortality were assessed in a cohort of 508 individuals living with HTLV‐1 followed over a 30‐year period. Overall mortality was 8.5% in this population and increased
Neves ES, Espíndola OM, Oliveira RVC, Leite ACCB, Lima MASD, Silva MTT, Osellame R, Guimarães PAP, Batista RV, Oliveira ALA, Araújo AQC.   +10 more
europepmc   +2 more sources

Physiotherapy Methods Applied in the Prevention of Functional Loss Associated with Human T-Lymphotropic Virus 1 Infection: An Overview

Infectious Disease Reports, 2023
To achieve the objective of this study, we conducted a narrative review on physical therapeutic modalities applied to prevent functional losses associated with human T-lymphotropic virus 1 (HTLV-1) infections to promote health education and viable and ...
Izabela Mendonça de Assis, Bianca Callegari, Maisa Silva de Sousa   +2 more
doaj   +1 more source

Syringohydromyelia or HTLV-I-associated myelopathy/tropical spastic paraparesis: a diagnostic challenge (case report) [PDF]

Arquivos de Neuro-Psiquiatria, 1999
Human T-cell lymphotropic virus type I (HTLV-I) associated myelopathy / tropical spastic paraparesis (HAM/TSP) is the most common chronic myelopathy in Brazil.
ABELARDO DE QUEIROZ-CAMPOS ARAÚJO, ANA CLAÚDIA CELESTINO BEZERRA LEITE, ANDRÉ LUIZ DOS ANJOS DE OLIVEIRA, CRISTIANE RIBEIRO DE ALMEIDA AFONSO, JULIANA PIES   +4 more
doaj   +1 more source

Caracterização molecular do HTLV-1 em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-1 em Belém, Pará Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará

Revista da Sociedade Brasileira de Medicina Tropical, 2006
O presente estudo avaliou a ocorrência da infecção pelo HTLV-1 e seus subtipos em amostras de sangue de pacientes com diagnóstico clínico de paraparesia espástica tropical/mielopatia associada ao Htlv-1.
Lucinda A. Souza, Ivina G.L. Lopes, Eduardo Leitão Maia, Vânia N. Azevedo, Luiz Fernando A. Machado, Marluísa O.G. Ishak, Ricardo Ishak, Antonio Carlos R. Vallinoto   +7 more
doaj   +1 more source

HTLV-1 and HIV-1 co-infection: A case report and review of the literature

IDCases, 2016
HTLV type 1 and 2 are both involved in actively spreading epidemics, affecting over 15 million people worldwide. HTLV-1 has been described as the more clinically significant one, being associated with diseases such as adult T-cell leukemia and tropical ...
Carmen Isache, Michael Sands, Nilmarie Guzman, Danisha Figueroa   +3 more
doaj   +1 more source