Results 11 to 20 of about 9,428 (208)

Urodynamic findings and vibegron effects on neurogenic lower urinary tract dysfunction caused by human T‐cell leukemia virus type I‐associated myelopathy/tropical spastic paraparesis [PDF]

IJU Case Reports
Introduction Human T‐cell lymphotropic virus type 1 infection can cause HTLV‐1‐associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary tract symptoms
Tomoyuki Kumekawa, Hidenori Akaihata, Hiroki Natsuya, Yuki Harigane, Hitomi Imai, Kanako Matsuoka, Ryo Tanji, Junya Hata, Soichiro Ogawa, Yoshiyuki Kojima   +9 more
doaj   +3 more sources

Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report [PDF]

Annals of Clinical and Translational Neurology
HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who ...
Jiahui Zeng, Wotu Tian, Jingran Yang, Yanping Yang, Li Cao, Xinghua Luan   +5 more
doaj   +3 more sources

Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis. [PDF]

J Neurovirol, 2020
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Nozuma S, Kubota R, Jacobson S.
europepmc   +2 more sources

Lived Experience of Human T-cell Leukemia Virus type-1 -Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP): A Phenomenology Study [PDF]

Iranian Journal of Medical Sciences
Background: Human T-cell Leukemia Virus type-1 (HTLV-1) -associated myelopathy causes sufferers to experience changes in several aspects of their lives.
Malihe Davoudi, Reza Boostani, Zahra Sadat Manzari   +2 more
doaj   +2 more sources

Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). [PDF]

Retrovirology, 2019
Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately 10–20 million people worldwide. While the majority of infected people are asymptomatic carriers of HTLV-1, only 4% of infected people develop HTLV-1-associated ...
Enose-Akahata Y, Jacobson S.
europepmc   +2 more sources

Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis [PDF]

Retrovirology, 2017
BackgroundAlthough human T-lymphotropic virus type 1 (HTLV-1) infection is a prerequisite for the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), specific provirus mutations in HAM/TSP have not yet been reported.
Satoshi Nozuma, Eiji Matsuura, Daisuke Kodama, Yuichi Tashiro, Toshio Matsuzaki, Ryuji Kubota, Shuji Izumo, Hiroshi Takashima   +7 more
openalex   +2 more sources

Cerebrospinal Fluid CXCL10 as a Candidate Surrogate Marker for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. [PDF]

Front Microbiol, 2019
Human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a debilitating, progressive disease without effective treatment; therefore, development of disease modifying therapy that improves long-term ...
Tamaki K, Sato T, Tsugawa J, Fujioka S, Yagishita N, Araya N, Yamauchi J, Coler-Reilly ALG, Nagasaka M, Hasegawa Y, Yamano Y, Tsuboi Y.   +11 more
europepmc   +2 more sources

Multiple spotty lesions of the spinal cord in a Chinese patient with human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis [PDF]

International Journal of Infectious Diseases, 2018
The case of a Chinese patient with human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP), who showed typical neurological symptoms of the disease, is reported here.
Hongzhi Gao, Xiang Ye, Ruowei Cai, Qiping Xu, Liping Liang, Shuji Izumo, Hui Qin Xing, Ryuji Kubota   +7 more
doaj   +2 more sources

Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan. [PDF]

Orphanet J Rare Dis, 2019
BackgroundAs human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neurological disease, large scale studies to collect continuous clinical data have been difficult to conduct ...
Tsutsumi S, Sato T, Yagishita N, Yamauchi J, Araya N, Hasegawa D, Nagasaka M, Coler-Reilly ALG, Inoue E, Takata A, Yamano Y.   +10 more
europepmc   +2 more sources

Functional capacity of natural killer cells in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. [PDF]

BMC Infect Dis, 2019
BackgroundNatural killer (NK) cells are part of the innate immune system and provide surveillance against viruses and cancers. The ability of NK cells to kill virus-infected cells depends on the balance between the effects of inhibitory and activating NK
Queiroz GAN, Mascarenhas REM, Vieillard V, Andrade RL, Galvão-Castro B, Grassi MFR.   +5 more
europepmc   +2 more sources