Results 31 to 40 of about 3,524 (151)

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy   +16 more
wiley   +1 more source

Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis. [PDF]

open access: yesPLoS ONE, 2014
HTLV-1 proviral loads (PVLs) and some genetic factors are reported to be associated with the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, there are very few reports on HAM/TSP having family history.
Satoshi Nozuma   +6 more
doaj   +1 more source

Viral Pathogens and Pulmonary Fibrosis: EMT‐Driven Mechanisms and Insights From Traditional Chinese Medicine

open access: yesReviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a serious progressive complication of the respiratory system, which is profoundly associated with persistent extracellular matrix (ECM) deposition, fibrosis, and disrupted tissue regeneration. Emerging evidence shows that epithelial–mesenchymal transition (EMT) acts as a key factor in the pathogenesis of ...
Ningzi Zang   +9 more
wiley   +1 more source

Assessment of Awareness and Knowledge Regarding Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Among Healthcare Workers at Imam Khomeini Hospital Complex, Tehran, in 2023–2024, A Cross‐Sectional Descriptive‐Analytical Study

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic Virus Type 1 (HTLV‐1), is responsible for serious diseases such as Adult T‐cell leukemia/lymphoma (ATLL) and HTLV‐1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). This research aimed to explore the level of awareness and knowledge of HTLV‐1 among healthcare professionals working at Imam ...
Arash Letafati   +8 more
wiley   +1 more source

Approach to a case of myeloneuropathy

open access: yesAnnals of Indian Academy of Neurology, 2016
Myeloneuropathy is a frequently encountered condition and often poses a diagnostic challenge. A variety of nutritional, toxic, metabolic, infective, inflammatory, and paraneoplastic disorders can present with myeloneuropathy. Deficiencies of vitamin B12,
Ravindra Kumar Garg   +2 more
doaj   +1 more source

HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Overlapping Ossification of the Ligamentum Flavum

open access: yesIndian Journal of Neurosurgery, 2020
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an important cause of nontraumatic and noncompressive chronic myelopathy which generally has no improvement regardless of treatment.
Guilherme Gago   +5 more
doaj   +1 more source

HTLV-1-associated myelopathy/tropical spastic paraparesis

open access: yesNature Reviews Disease Primers, 2015
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the legs, lower back pain and urinary symptoms. HAM/TSP was first described in Jamaica in the nineteenth century, but the aetiology of the condition, infection with the retrovirus ...
Bangham, CRM   +3 more
openaire   +4 more sources

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

open access: yesCancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

HTLV-I associated myelopathy / tropical spastic paraparesis: report of the first cases in Rio Grande do Sul, Brazil Mielopatia associada ao HTLV-I/paraparesia espástica tropical: relato dos primeiros casos no Rio Grande do Sul, Brasil

open access: yesArquivos de Neuro-Psiquiatria, 1995
The HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a myelopathy with predominant involvement of the pyramidal tract with minimal sensory loss and associated with HTLV-I infection, endemic in tropical areas, has been identified in ...
Sérgio Roberto Haussen   +1 more
doaj   +1 more source

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