Results 31 to 40 of about 9,428 (208)

Tropical Spastic Paraparesis [PDF]

Definitions, 2019
TSP was initially described in tropical countries but has now also been identified in temperate countries (eg, southern Japan) as HTLV-1-associated myelopathy (HAM).
openaire   +2 more sources

HTLV-1-associated myelopathy/tropical spastic paraparesis

Nature Reviews Disease Primers, 2015
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the legs, lower back pain and urinary symptoms. HAM/TSP was first described in Jamaica in the nineteenth century, but the aetiology of the condition, infection with the retrovirus ...
Bangham, CRM, Araujo, A, Yamano, Y, Taylor, GP   +3 more
openaire   +5 more sources

Visualization of HTLV-1–Specific Cytotoxic T Lymphocytes in the Spinal Cords of Patients With HTLV-1–Associated Myelopathy/Tropical Spastic Paraparesis [PDF]

Journal of Neuropathology and Experimental Neurology, 2014
Activated human T-lymphotropic virus type-1 (HTLV-1)–specific CD8-positive cytotoxic T lymphocytes (CTLs) are markedly increased in the periphery of patients with HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP), an HTLV-1–induced ...
Eiji Matsuura, Ryuji Kubota, Yuetsu Tanaka, Hiroshi Takashima, Shuji Izumo   +4 more
openalex   +2 more sources

The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study [PDF]

Reviews in Clinical Medicine, 2019
Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Masoud Keikha, mohsen Karbalaei Zadeh Babaki, Luiz Augusto Marcondes Fonseca, Jorge Casseb   +3 more
doaj   +2 more sources

Therapeutic effects of virtual reality video gaming on functional mobility, balance, and gait speed in individuals with tropical spastic paraparesis: A randomized crossover clinical trial. [PDF]

Rev Soc Bras Med Trop, 2021
Fonseca EPD, Sá KN, Nunes RFR, Souza CRJ, Sousa MCM, Pinto EB.   +5 more
europepmc   +2 more sources

Gut Microbiome Dysbiosis is Associated With Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection and Disease Progression to HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Cross-Sectional Study. [PDF]

Smart Med
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Fernandes LA, de Souza AO, Nukui Y, Marcusso RM, de Oliveira ACP, Casseb J, Clissa PB, Villas-Boas SG, Sanabani SS.   +8 more
europepmc   +2 more sources

Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study [PDF]

Neurotherapeutics, 2017
Ariella Coler‐Reilly, Tomoo Sato, Toshio Matsuzaki, Masanori Nakagawa, Masaaki Niino, Masahiro Nagai, Tatsufumi Nakamura, Norihiro Takenouchi, Natsumi Araya, Naoko Yagishita, Eisuke Inoue, Yoshihisa Yamano   +11 more
openalex   +2 more sources

Dermatologic Manifestations in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

Acta Medica Iranica, 2019
The human T cell lymphotropic virus type-1 (HTLV-1) is associated with adult T cell leukemia/lymphoma (ATL) and other disorders, including a slowly progressive demyelinating paraparesis, known as HTLV-1-associated myelopathy/tropical spastic paraparesis (
Reza Boostani, Pouran Layegh, Mohammad Javad Yazdanpanah, Elham Vosoughi, Azadeh Mohammadi, Noseibe Joneidi, Reyhaneh Bazargani, Delaram Sayadpour Zanjani, Saeed Ebrahimzadeh   +8 more
doaj   +2 more sources

Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. [PDF]

J Med Virol
ABSTRACT Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurodegenerative disease affecting motor and sensory functions. While alterations in cerebrospinal fluid (CSF) have been used to identify disease biomarkers, the effects of such modified CSF on CNS cells remain unexplored.
Gomes YCP, Bongers A, Jeannin P, Vicente ACP, Gessain A, Afonso PV, Espindola OM.   +6 more
europepmc   +2 more sources

Progression of HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis after Pregnancy: A Case Series and Review of the Literature. [PDF]

Pathogens
Jacquerioz FA, La Rosa M, González-Lagos E, Alvarez C, Tipismana M, Luhmann K, Gotuzzo E.   +6 more
europepmc   +3 more sources