Results 51 to 60 of about 3,524 (151)

Enhancing Crop Nutrition in Arid and Semiarid Regions of Africa Through Genome Editing Using CRISPR/Cas

Food and Energy Security, Volume 14, Issue 3, May/June 2025.
ABSTRACT Food insecurity is a pressing issue in Africa, aggravated by escalating drought, jeopardizing the region's ability to meet nutritional requirements for human health. In arid and semiarid regions, crop yield is severely affected by drought and salinity.
Erick Amombo, Rita H. Mumm, Abdelaziz Nilahyane, Abdelaziz Hirich, Mohamed Hijri, Valentine Otang Ntui   +5 more
wiley   +1 more source

Rewired chromatin structure and epigenetic gene dysregulation during HTLV‐1 infection to leukemogenesis

Cancer Science, Volume 116, Issue 2, Page 513-523, February 2025.
We analyzed and evaluated cells infected with human T‐cell leukemia virus type 1 at different stages of infection in terms of gene expression and chromatin structure using ATAC sequencing and RNA sequencing. Our results revealed that infected cells exhibited significant changes in gene expression patterns from the polyclonal stage and before adult T ...
Jun Mizuike, Kako Suzuki, Shu Tosaka, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Koji Jimbo, Yasuhito Nannya, Yutaka Suzuki, Kaoru Uchimaru, Makoto Yamagishi   +10 more
wiley   +1 more source

Human T‐Lymphotropic Virus Type 1–Associated Myelopathy With Autoimmune Cholangiopathy: An Unusual Immune Conundrum in a Young Patient

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Human​ T‐lymphotropic virus type 1 (HTLV‐1), the first oncogenic retrovirus discovered in humans, is primarily associated with two disease entities: adult T cell leukemia‐lymphoma and HTLV‐1‐associated myelopathy‐tropical spastic paresis. HTLV‐1 has also been implicated in the pathogenesis of various autoimmune rheumatic diseases, and its association ...
Aida Saad, Yamna Jadoon, Riffat Sabir, Piyush Baindara   +3 more
wiley   +1 more source

Stability and Perpetuation of Human T‐Lymphotropic Virus 1 (HTLV‐1) in Intrafamilial Transmissions of Infection in an Endemic Region of the Brazilian Amazon: A Pilot Study

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Introduction Human T‐lymphotropic virus 1 (HTLV‐1) is related to several clinical diseases, including adult T‐cell leukemia/lymphoma and HTLV‐1‐associated myelopathy. Intrafamilial transmission of HTLV‐1 is rarely reported in Brazil and worldwide. Objective To identify HTLV‐1 family transmissions in Belem, Para, the Amazon region of Brazil.
Cássia Cristine Costa Pereira, Milena Cristina Martins da Silva, Samir Mansour Moraes Casseb, Maria de Nazaré Lima dos Reis, Louise de Souza Canto Covre, Edna Aoba Yassui Ishikawa, Leonardo Miranda dos Santos, Carlos Araújo da Costa, Maisa Silva de Sousa, Rajib Chowdhury   +9 more
wiley   +1 more source

HTLV-1 antibodies in serum and cerebrospinal fluid in tropical spastic paraparesis in Brazil

Arquivos de Neuro-Psiquiatria, 1990
HTLV-l antibodies were investigated in serum and in CSF of 150 patients with neurologic disorders mainly myelopathies. The patients were considered into three groups according to the possible relationship of their disease to the presence of HTLV-l ...
A. Spina-França, J. A. Livramento, L. R. Machado, H. R. Gomes, L. S. Vianna, L. H. M. Castro, J. P. S. Nobrega, L. A. Baciheschi   +7 more
doaj   +1 more source

Evidence of preferential female prevalence of HTLV-I associated tropical spastic paraparesis in Bahia-Brazil

Arquivos de Neuro-Psiquiatria, 1992
In order to evaluate the prevalence of HTLV-I infection and its association with tropical spastic paraparesis (TSP) in Bahia, a Northeastern State of Brazil, CSF and sera from TSP patients and CSF and/or sera from some selected groups of individuals were
O. A. Moreno-Carvalho, J. I. Santos, G. Di Credico, B. Galvão-Castro   +3 more
doaj   +1 more source

Strengthening awareness and response to HTLV‐1 infection in Africa: A neglected threat to blood safety and public health

HemaSphere, Volume 9, Issue 10, October 2025.
Jean‐Claude Twizere, Carolina Rosadas, Maureen Kidiga, Fatumata Djalo, Edward L. Murphy, Augustin Mouinga‐Ondeme, Marion Vermeulen, Louine Morrell, Saliou Diop, Sibusiso Maseko, Peregrine Sebulime, Andrews Akwasi Agbleke, Boineelo Fundisi, Espérance Umumararungu, Patricia Watber, Carol Hlela, Egídio Nhavene, Thato Chidarikire, Olivier Hermine, Antoine Gessain   +19 more
wiley   +1 more source

HTLV-I Associated uveitis, myelopathy, rheumatoid arthritis and Sjögren's syndrome Uveite, mielopatia, artrite reumatóide e sindrome de Sjogren associadas ao HTLV-I

Arquivos de Neuro-Psiquiatria, 1995
A 62 year-old white female presented with a 10-year-history of slowly progressive spastic paraparesis, pain and dysesthesia in the lower limbs and sphincter disturbance.
Sônia Regina A. A. Pinheiro, Marco Aurélio Lana-Peixoto, Anna B. Carneiro Proietti, Fernando Oréfice, Maria V. Lima-Martins, Fernando A. Proietti   +5 more
doaj   +1 more source

Proprioceptive neuromuscular facilitation in HTLV-I-associated myelopathy/tropical spastic paraparesis

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Introduction: Human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) can impact the independence and motricity of patients.
Vera Lúcia Santos de Britto, Rosalie Correa, Maurice Borges Vincent   +2 more
doaj   +1 more source

HTLV-I Associated myelopathy in porto alegre (southern Brazil) Mielopatia associada ao HTLV-I em Porto Alegre (Sul do Brasil)

Arquivos de Neuro-Psiquiatria, 1995
HTLV-I associated myelopathy/tropical spastic paraparesis (TSP/HAM) have been increasingly described in practically all regions of Brazil. Five confirmed and documented cases of patients with TSP/HAM in Rio Grande do Sul are reported; in all of them ...
Márcio Menna-Barreto, Alexandre Doval, Giorgio Rabolin, Otomar Bianchini   +3 more
doaj   +1 more source