Results 61 to 70 of about 9,428 (208)

Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis. [PDF]

PLoS ONE, 2014
HTLV-1 proviral loads (PVLs) and some genetic factors are reported to be associated with the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, there are very few reports on HAM/TSP having family history.
Satoshi Nozuma, Eiji Matsuura, Toshio Matsuzaki, Osamu Watanabe, Ryuji Kubota, Shuji Izumo, Hiroshi Takashima   +6 more
doaj   +1 more source

Pain and Quality of Life in Human T-cell Lymphotropic Virus Type 1-Associated Myelopathy or Tropical Spastic Paraparesis After Home-Based Exercise Protocol: A Randomized Clinical Trial.

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION Human T-cell lymphotropic virus type 1-associated myelopathy or tropical spastic paraparesis (HAM/TSP) causes, among other abnormalities, chronic pain that may impair quality of life (QOL).
M. Macêdo, Renata de Sousa Mota, N. Patrício, A. Baptista, Antônio de Souza Andrade Filho, K. Sá   +5 more
semanticscholar   +1 more source

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

Cancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

Drivers of Grass Pea (Lathyrus sativus L.) Market Supply and Its Sustainability Payoffs: Evidence From Jama District, Ethiopia

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Grass pea (Lathyrus sativus L.) is a climate‐smart legume crop widely grown in Ethiopia, well‐known for its resilience to abiotic stresses, and serves as an insurance crop. Despite its ecological and agronomic benefits, the crop's market supply remains underexplored from both economic and sustainability perspectives.
Yosef Worku Yigezu, Zenebu Shewakena Sidell, Tessema Astatkie   +2 more
wiley   +1 more source

Approach to a case of myeloneuropathy

Annals of Indian Academy of Neurology, 2016
Myeloneuropathy is a frequently encountered condition and often poses a diagnostic challenge. A variety of nutritional, toxic, metabolic, infective, inflammatory, and paraneoplastic disorders can present with myeloneuropathy. Deficiencies of vitamin B12,
Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar   +2 more
doaj   +1 more source

HTLV-I associated myelopathy / tropical spastic paraparesis: report of the first cases in Rio Grande do Sul, Brazil Mielopatia associada ao HTLV-I/paraparesia espástica tropical: relato dos primeiros casos no Rio Grande do Sul, Brasil

Arquivos de Neuro-Psiquiatria, 1995
The HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a myelopathy with predominant involvement of the pyramidal tract with minimal sensory loss and associated with HTLV-I infection, endemic in tropical areas, has been identified in ...
Sérgio Roberto Haussen, Maria Cecilia de Vecino   +1 more
doaj   +1 more source

PERFORMANCE OF THE GAIT IN INDIVIDUALS WITH HTLV-1: SYSTEMATIC REVIEW

Revista Pesquisa em Fisioterapia, 2017
HTLV-1 is frequently associated with myelopathy/tropical spastic paraparesis (HAM/TSP), which in turn brings several functional alterations to the individual, including changes in gait.
Mateus Evangelista do Amparo Santana, Livia Aguiar Pereira, Rafael Monteiro, Erika Pedreira Fonseca   +3 more
doaj   +1 more source

Tropical spastic paraparesis.

Folia neuropathologica, 2002
Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases.
J, Buczyński, R, Yanagihara, C, Mora, L, Cartier, A, Verdugo, F, Araya, L, Castillo, C J, Gibbs, C D, Gajdusek, P, Rogers-Johnson, P P, Liberski   +10 more
openaire   +1 more source

Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition

Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.
ABSTRACT Extracellular vesicles (EVs) are known to facilitate infection by enveloped RNA viruses including the Human T‐cell leukemia virus type‐1 (HTLV‐1). HTLV‐1‐encoded proteins, like the transactivator and oncoprotein Tax‐1, are loaded into EVs but their precise impact on EV cargos is not yet known.
Jedidja Puttemans, Yasmine Brammerloo, Karim Blibek, Jeremy Blavier, Thandokuhle Ntombela, Inge Van Molle, Julie Joseph, Julien Olivet, Deeya Saha, Manon Degey, Malik Hamaidia, Pooja Jain, Piel Geraldine, Pascale Zimmermann, Dae‐Kyum Kim, Dominique Baiwir, Makon‐Sébastien Njock, Franck Dequiedt, Kourosh Salehi‐Ashtiani, Steven Ballet, Alexander N. Volkov, Jean‐Claude Twizere, Sibusiso B. Maseko   +22 more
wiley   +1 more source