Results 111 to 120 of about 7,724 (232)
Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas [PDF]
, 2014 Abdominal aortic aneurysms (AAAs) cause death due to complications related to expansion and rupture. The underlying mechanisms that drive AAA development remain largely unknown. We recently described evidence for a shift toward T helper type 2 (Th2) cell
Lee, Richard Theodore +4 more
core +1 more source
Biotechnology Progress, Volume 41, Issue 6, November/December 2025.Abstract Elastin‐like polypeptides (ELPs) are recombinant protein‐like polymers whose macromolecular structure can be precisely controlled through genetic manipulation of their sequence and length. Their lower critical solution temperature (LCST) phase behavior facilitates purification via chromatography‐free techniques and can be explored for self ...
Alice Delhaes +4 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyBackground: Osteoarthritis (OA) is a debilitating degenerative joint disease, leading to significant pain and disability. Despite advancements, current regenerative therapies, such as mesenchymal stem cells (MSCs), face challenges in clinical efficacy ...
Junjun Yang +11 more
doaj +1 more source
A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]
, 2008 Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox, Michael A. +3 more
core +4 more sources
Bioengineered vascular scaffolds: the state of the art [PDF]
, 2014 To date, there is increasing clinical need for vascular substitutes due to accidents, malformations, and ischemic diseases. Over the years, many approaches have been developed to solve this problem, starting from autologous native vessels to artificial ...
Bruno, A +4 more
core +1 more source
Hepatology Research, Volume 55, Issue 11, Page 1425-1436, November 2025.ABSTRACT Chronic liver diseases (CLD) arising from various etiologies including viral hepatitis, excessive alcohol intake, alcoholic associated liver disease (ALD) and metabolic dysfunction‐associated steatotic liver disease (MASLD), are associated with persistent hepatic injury ultimately resulting in fibrosis.
Fidaa Bouezzedine +2 more
wiley +1 more source
Tunable, Temperature-Responsive Polynorbornenes with Side Chains Based on an Elastin Peptide Sequence [PDF]
, 2009 Random copolymers made by living ring-opening metathesis polymerization of norbornene monomers containing either the elastin peptide sequence -(VPGVG)- or pentaethylene glycol (see scheme; Mes=mesityl, pyr=pyridine) exhibit a lower critical solution ...
Conrad, Rosemary M., Grubbs, Robert H.
core +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
FEBS Open Bio, Volume 15, Issue 10, Page 1552-1569, October 2025.The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source
Amyloidogenesis of proteolytic fragments of human elastin [PDF]
, 2013 Some polypeptides encoded by the C-terminal region of human tropoelastin gene have been demonstrated to be amyloidogenic in vitro. The biological relevance of this finding is still under investigation given that only limited evidence concerning the ...
Baud, Stéphanie +5 more
core +3 more sources
Advanced Science, Volume 12, Issue 40, October 27, 2025.An injectable, photocrosslinkable hydrogel sealant—comprising GelMAG, DMA, and pDDA—demonstrated strong underwater adhesion, elasticity, biocompatibility, and broad‐spectrum antibacterial activity. This material rapidly sealed dynamic internal organ injuries and significantly reduced blood loss in vivo. Its superior performance over commercial products
Saumya Jain +6 more
wiley +1 more source