Results 111 to 120 of about 6,608 (237)

Tunable, Temperature-Responsive Polynorbornenes with Side Chains Based on an Elastin Peptide Sequence [PDF]

open access: yes, 2009
Random copolymers made by living ring-opening metathesis polymerization of norbornene monomers containing either the elastin peptide sequence -(VPGVG)- or pentaethylene glycol (see scheme; Mes=mesityl, pyr=pyridine) exhibit a lower critical solution ...
Conrad, Rosemary M., Grubbs, Robert H.
core   +1 more source

Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

open access: yes, 2020
Arterial tortuosity syndrome (ATS) is a recessively inherited connective tissue disorder, mainly characterized by tortuosity and aneurysm formation of the major arteries.
Barnhoorn, Sander   +14 more
core   +1 more source

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

open access: yes, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J   +5 more
core   +3 more sources

Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins

open access: yesCancer Medicine, Volume 14, Issue 1, January 2025.
This review comprehensively covers the TRAIL fusion proteins that have been reported in recent years. It also summarizes six commonly employed strategies used in the construction of TRAIL fusion proteins. ABSTRACT Background TNF‐related apoptosis‐inducing ligand (TRAIL) belongs to the tumor necrosis factor superfamily.
Yan Wang   +7 more
wiley   +1 more source

Amyloidogenesis of proteolytic fragments of human elastin [PDF]

open access: yes, 2013
Some polypeptides encoded by the C-terminal region of human tropoelastin gene have been demonstrated to be amyloidogenic in vitro. The biological relevance of this finding is still under investigation given that only limited evidence concerning the ...
Baud, Stéphanie   +5 more
core   +3 more sources

A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair

open access: yesMaterials Today Bio, 2020
Pelvic organ prolapse is a common condition that affects 1 in 4 women across all age groups. It is mainly caused by vaginal birth injury and can be exacerbated by obesity and increased age.
B. Aghaei-Ghareh-Bolagh   +8 more
doaj  

Tropoelastin improves adhesion and migration of intra-articular injected infrapatellar fat pad MSCs and reduces osteoarthritis progression

open access: yesBioactive Materials, 2022
Intra-articular injection of mesenchymal stem cells (MSCs) is a promising strategy for osteoarthritis (OA) treatment. However, more and more studies reveal that the injected MSCs have poor adhesion, migration, and survival in the joint cavity.
Junjun Yang   +15 more
doaj  

Elastin-based biopolymers for biomedical and biotechnological applications [PDF]

open access: yes, 2014
Perhaps the most appealing opportunity is represented by gaining inspiration from nature for the precise tailoring of biomaterials with finely tuned unique functional properties.
Bandiera, Antonella
core   +1 more source

Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

open access: yesMatrix Biology Plus, 2021
Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in collagen fibers. Type VIII collagen
Amanda L. Mohabeer   +13 more
doaj  

Fibrillin-Rich Microfibrils are Reduced in Photoaged Skin. Distribution at the Dermal–Epidermal Junction [PDF]

open access: yes, 1999
Chronic sun exposure results in photoaged skin with deep coarse wrinkles and loss of elasticity. We have examined the distribution and abundance of fibrillin-rich microfibrils, key structural components of the elastic fiber network, in photoaged and ...
Craven, Nicholas M.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy