Results 111 to 120 of about 9,068 (269)

Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc [PDF]

, 2016
The aim of this study was to immunolocalise type VI collagen and perlecan and determine their interactive properties in the intervertebral disc (IVD).
AJ Hayes, CB Little, CC Shu, J Melrose, JM Whitelock, MS Lord, null null   +6 more
core   +3 more sources

Engineering Aging: Approaches to Model and Deconstruct Biological Complexity

Advanced Materials, Volume 38, Issue 1, 2 January 2026.
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar, Sunny Shinchen Lee, Thomas R. Cox, Yu Suk Choi, Steven G. Wise, Jennifer L. Young, Giselle C. Yeo, Khoon S. Lim   +7 more
wiley   +1 more source

Bio‐inspired functional coacervates

Aggregate, 2022
Many functional coacervates have been identified in biological systems, which have attracted widespread interest. Coacervation is a liquid–liquid phase separation (LLPS) process in which a macromolecule‐enriched liquid phase is formed together with a ...
Shujun Chen, Qi Guo, Jing Yu
doaj   +1 more source

Wound dressings for a proteolytic-rich environment [PDF]

, 2011
Wound dressings have experienced continuous and significant changes over the years based on the knowledge of the biochemical events associated with chronic wounds.
A Hinek, A Hinek, A Hinek, A Schneider, A Tachibana, A Vasconcelos, AF Falabella, AF Morey, AJ Kuijpers, AM Breen, Andreia Vasconcelos, AP Negri, AR Fitton, AR Halbert, Artur Cavaco-Paulo, AY Mensah, B Balakrishnan, B Balakrishnan, B Balakrishnan, B Cullen, B Hafemann, B Panilaitis, BAC Harley, BB Mandal, BB Mandal, BC Griffith, BM Kuehn, C Buchta, C Earland, C Martyn, C Wong Po Foo, C Yang, C Yang, C-M Deng, C-M Ding, C-Z Zhou, CH Lee, CH Yao, CJ Doillon, CJ Doillon, CM Bellingham, CZ Zhou, D Berry, D Gopinath, D Huemmerich, D Le Nihouannen, D Michel, D Queen, DAD Parry, DC Daltrey, DJ Smith, DJ Vachon, DL Kaplan, DL Kaplan, DR Eyre, DR Goddard, DW Urry, E Rossitch, E Wright, EA Yücel, EN Lamme, EN Lamme, F Auger, F Breinl, F Strodtbeck, F Vollrath, FJ O’Brien, G Chen, G Chen, G Faury, G Man, G Wechselberger, GH Altman, GS Lazarus, H Bannasch, H De Vries, H Schmoekel, H-J Jin, HJ Jin, HM Powell, HM Powell, I Grant, I Ono, I Ono, I Pasquali-Ronchetti, IC Um, III Bidwell, IJ O’Donnell, J Lee, J Lee, J Oju, J Reguera, J Rosenbloom, J-P Chen, J-T Schantz, JA Maclaren, JE Plowman, JH Buchanan, JL Long, JN Kearney, JP Nicholas, JS Boateng, K Hori, K Inngjerdingen, K Kawai, K Kawai, K Madsen, K Ulubayram, KF Cutting, KG Harding, KS Rho, L Duca, LF Drummy, LR Moy, M Ehrbar, M Feughelmann, M Yamamoto, MB Dainiak, MJ Humphries, MJ McClure, MP Curran, MP Jacob, MR Neidert, MS Kumar, MW Dunn, N Adhirajan, NT Dai, PG Bowler, PG Bowler, PG Bowler, PH Jørgensen, PPM van Zuijlen, Q Lu, R Herrero-Vanrell, R Okabayashi, R Ross, R Sanjay, RE Unger, RL Horan, RL Reis, RMZ Farahani, RP Mecham, S Ayad, S Hamasaki, S Hofmann, S Huang, S Inoue, S Thilagar, S Thomas, S Winkler, S-J Liu, S-Y Gu, SA Wood, SC Sehgal, SE Gardner, SK Purna, SM Baughman, SM Mithieux, SM Partridge, SM Willerth, SP Zhong, T Aper, T Hashimoto, T Hino, T Kitajima, T-W Wang, U Schönfelder, UR Shettigar, V Verma, W Haslik, W Haslik, W Jiang, W Thomas, W Wang, WF Daamen, WG Crewther, WS Douglas, WYJ Chen, X Wang, Y Garcia, Y Ikada, Y Wang, Y-Q Zhang, YH Chen, YH Chen, Z Ruszczak, Z Wu   +186 more
core   +1 more source

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

The FEBS Journal, Volume 293, Issue 2, Page 418-442, January 2026.
We analysed collagen XV expression in myocardial infarct samples and assessed how its deficiency affects cardiac responses, such as fibrogenesis and tissue stiffness. In mice, damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel ...
Sanna‐Maria Karppinen, Miki Aho, Zoltan Szabo, Johanna Magga, Laura Vainio, Erhe Gao, Paul Janmey, Lauri Eklund, Karolina Rasi, Ilkka Miinalainen, Lynn Y. Sakai, Lasse Pakanen, Heikki Huikuri, Juhani Junttila, Risto Kerkelä, Taina Pihlajaniemi   +15 more
wiley   +1 more source

Mechanistic Insight into the Elastin Degradation Process by the Metalloprotease Myroilysin from the Deep-Sea Bacterium Myroides profundi D25

Marine Drugs, 2015
Elastases have been widely studied because of their important uses as medicine and meat tenderizers. However, there are relatively few studies on marine elastases. Myroilysin, secreted by Myroides profundi D25 from deep-sea sediment, is a novel elastase.
Jie Yang, Hui-Lin Zhao, Bai-Lu Tang, Xiu-Lan Chen, Hai-Nan Su, Xi-Ying Zhang, Xiao-Yan Song, Bai-Cheng Zhou, Bin-Bin Xie, Anthony S. Weiss, Yu-Zhong Zhang   +10 more
doaj   +1 more source

Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils [PDF]

, 2017
Producción CientíficaBiomineralization of bone, a controlled process where hydroxyapatite nanocrystals preferentially deposit in collagen fibrils, is achieved by the interplay of the collagen matrix and noncollagenous proteins.
Aparicio, Conrado, Li, Yuping, Rodríguez Cabello, José Carlos   +2 more
core   +3 more sources

Molecular model of human tropoelastin and implications of associated mutations

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Tropoelastin, the precursor molecule to elastic fibers, is a large, flexible elastic protein whose structure has been the subject of investigation and debate over several decades.
A. Tarakanova, Giselle C. Yeo, C. Baldock, A. Weiss, M. Buehler   +4 more
semanticscholar   +1 more source

How the Fibrotic Lung Microenvironment Regulates Stem Cell Behavior: Immune Cues, Extracellular Matrix Remodeling, and Therapeutic Implications

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease characterized by excessive extracellular matrix (ECM) deposition and remodeling of lung structures. Currently, no effective clinical treatments exist to reverse or halt the progression of PF.
Zihan Zhou, Shuhua Han, Yuanfang Duan, Minqi Hong, Jie Huang, Andrey Elchaninov   +5 more
wiley   +1 more source

Comparison of ex vivo and in vitro human fibroblast ageing models [PDF]

, 2010
Several studies have analyzed modulation of gene expression during physiological ageing with interesting, but often contradictory results, depending on the model used.
ANNOVI, Giulia, BORALDI, Federica, QUAGLINO, Daniela, Sommer, P., TIOZZO, Roberta   +4 more
core   +1 more source