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Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal. [PDF]
Zhang N +9 more
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Combining genome and tissue engineering for next-generation human biomimetics. [PDF]
Gähwiler EKN +7 more
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The International Journal of Biochemistry & Cell Biology, 2009
Tropoelastin is a 60-72 kDa alternatively spliced extracellular matrix protein and a key component of elastic fibres. It is found in all vertebrates except for cyclostomes. Secreted tropoelastin is tethered to the cell surface, where it aggregates into organised spheres for cross-linking and incorporation into growing elastic fibres.
Steven G, Wise, Anthony S, Weiss
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Tropoelastin is a 60-72 kDa alternatively spliced extracellular matrix protein and a key component of elastic fibres. It is found in all vertebrates except for cyclostomes. Secreted tropoelastin is tethered to the cell surface, where it aggregates into organised spheres for cross-linking and incorporation into growing elastic fibres.
Steven G, Wise, Anthony S, Weiss
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Advances in Colloid and Interface Science, 2011
The coacervation of tropoelastin represents the first major stage of elastic fiber assembly. The process has been modeled in vitro by numerous studies, initially with mixtures of solubilized elastin, and subsequently with synthetic elastin peptides that represent hydrophobic repeat units, isolated hydrophobic domains, segments of alternating ...
Giselle C, Yeo +2 more
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The coacervation of tropoelastin represents the first major stage of elastic fiber assembly. The process has been modeled in vitro by numerous studies, initially with mixtures of solubilized elastin, and subsequently with synthetic elastin peptides that represent hydrophobic repeat units, isolated hydrophobic domains, segments of alternating ...
Giselle C, Yeo +2 more
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Properties of chick tropoelastin
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1973Abstract 1. 1. Tropoelastin was purified from the aortas of copper-deficient chicks. The amino acid composition of this protein is very similar to that previously described for porcine tropoelastin. The protein contains more than 40 residues of lysine per thousand total residues and no desmosine or isodesmosine. 2. 2.
R B, Rucker +2 more
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Intracellular trafficking of tropoelastin
Matrix Biology, 1998Elastin is secreted as soluble tropoelastin monomers which are then cross-linked in the presence of extracellular microfibrils to form insoluble elastic fibers. Although the secretion of tropoelastin is thought to be mediated and targeted by an intracellular chaperone complex, the intracellular route taken by this protein and the role of such a ...
E C, Davis, R P, Mecham
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1977
The presence of an enzyme associated with tropoelastin is described. The enzyme has a pH optimum between 7 and 9 and trypsin-like specificity. Upon incubation, tropoelastin (72,000 molecular weight) is cleaved into relatively high molecular weight fragments. In addition to the parent molecule, five discrete polypeptide bands are usually observed on SDS
R, Mecham, J A, Foster, C, Franzblau
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The presence of an enzyme associated with tropoelastin is described. The enzyme has a pH optimum between 7 and 9 and trypsin-like specificity. Upon incubation, tropoelastin (72,000 molecular weight) is cleaved into relatively high molecular weight fragments. In addition to the parent molecule, five discrete polypeptide bands are usually observed on SDS
R, Mecham, J A, Foster, C, Franzblau
openaire +2 more sources

