Results 41 to 50 of about 4,779 (198)
Extracellular Matrix Molecules Facilitating Vascular Biointegration
Journal of Functional Biomaterials, 2012 All vascular implants, including stents, heart valves and graft materials exhibit suboptimal biocompatibility that significantly reduces their clinical efficacy.
Martin K.C. Ng +3 more
doaj +1 more source
A novel tropoelastin-based resorbable surgical mesh for pelvic organ prolapse repair
Materials Today Bio, 2020 Pelvic organ prolapse is a common condition that affects 1 in 4 women across all age groups. It is mainly caused by vaginal birth injury and can be exacerbated by obesity and increased age.
B. Aghaei-Ghareh-Bolagh +8 more
doaj +1 more source
Bioactive Materials, 2022 Intra-articular injection of mesenchymal stem cells (MSCs) is a promising strategy for osteoarthritis (OA) treatment. However, more and more studies reveal that the injected MSCs have poor adhesion, migration, and survival in the joint cavity.
Junjun Yang +15 more
doaj +1 more source
Multifunctional SilkTropoelastin Biomaterial Systems [PDF]
Israel Journal of Chemistry, 2013 AbstractNew multifunctional, degradable, polymeric biomaterial systems would provide versatile platforms to address cell and tissue needs in both in vitro and in vivo environments. While protein‐based composites or alloys are the building blocks of biological organisms, similar systems have not been largely exploited, to date, to generate ad hoc ...
Chiara E, Ghezzi +3 more
openaire +2 more sources
Tropoelastin-Inspired, Non-Ionic, Self-Coacervating Polyesters as Strong Underwater Adhesives
, 2019 Inspired from the one-component self-coacervation of tropoelastin and mussel foot protein-3s, we created the first non-ionic, single component coacervates that can coacervate in a all ranges of pH (acidic to basic) and wide range of ionic strengths with ...
Amal Narayanan (7471625) +4 more
core +1 more source
Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. [PDF]
PLoS ONE, 2013 Recent work has uncovered a role of the microRNA (miRNA) miR-29 in remodeling of the extracellular matrix. Partial bladder outlet obstruction is a prevalent condition in older men with prostate enlargement that leads to matrix synthesis in the lower ...
Mari Ekman +5 more
doaj +1 more source
Tropoelastin Massively Associates during Coacervation To Form Quantized Protein Spheres†
, 2016 Tropoelastin, the precursor of elastin, undergoes a rapid monomer to multimer association in an inverse temperature transition. This association culminates in the rapid formation of stable, optically distinct droplets of tropoelastin.
Suzanne M. Mithieux (2530846) +5 more
core +6 more sources
Structural studies of elastic fibre and microfibrillar proteins
Matrix Biology Plus, 2021 Elastic tissues owe their functional properties to the composition of their extracellular matrices, particularly the range of extracellular, multidomain extensible elastic fibre and microfibrillar proteins.
Mukti Singh +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2017 Leptospira immunoglobulin-like protein B (LigB), a surface adhesin, is capable of mediating the attachment of pathogenic leptospira to the host through interaction with various components of the extracellular matrix (ECM).
Ching-Lin Hsieh +6 more
doaj +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source