Results 71 to 80 of about 6,608 (237)
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio+7 more
wiley +1 more source
Glucocorticoid Regulation of Elastin Synthesis in Human Fibroblasts: Down-Regulation in Fibroblasts from Normal Dermis But Not From Keloids [PDF]
Keloids arise as benign connective tissue masses at sites of injury in genetically predisposed individuals, In addition to excessive collagen accumulation, there is biochemical and histologic evidence of elastic tissue.
Davidson, Jeffrey M.+4 more
core +1 more source
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai+5 more
wiley +1 more source
Topical Tretinoin Increases the Tropoelastin and Fibronectin Content of Photoaged Hairless Mouse Skin [PDF]
Topical tretinoin treatment of photoaged hairless mice has been shown in previous studies to stimulate formation of a subepidermal zone of new connective tissue characterized by enhanced collagen synthesis.
Kligman, Lorraine H., Schwartz, Elaine
core +1 more source
Impact of N‐linked glycans on the dual short fibulin/LTBP‐4 axes regulating elastogenesis
Elastic fiber assembly is orchestrated by multiple glycoproteins. We delineate the molecular basis of two key axes involved in elastic fiber formation—LTBP‐4L/fibulin‐4 and LTBP‐4S/fibulin‐5. We show that N‐linked glycans on these glycoproteins regulate their interactions and conformations, both of which are critical aspects in elastic fiber formation.
Valentin Nelea+8 more
wiley +1 more source
PKCε Increases Extracellular Elastin and Fibulin-5/DANCE in Dermal Fibroblasts
Background/Aims: In the earlier study, the selective PKCε activator DCP-LA increased elastic fibres in the dermis of HR-1 hairless mice. As a process of elastic fibre formation, tropoelastin, an elastin monomer, is secreted into the extracellular space ...
Tomoyuki Nishizaki
doaj +1 more source
Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils [PDF]
Producción CientíficaBiomineralization of bone, a controlled process where hydroxyapatite nanocrystals preferentially deposit in collagen fibrils, is achieved by the interplay of the collagen matrix and noncollagenous proteins.
Aparicio, Conrado+2 more
core +3 more sources
Self‐assembly of short biopeptides onto skin tissue components studied using QCM‐D
An understanding of the interactions of the skin care products with skin tissue will enable rational design more effective products. We show the use of Quartz Crystal Microbalance with Dissipation (QCM‐D) to monitor in real time the adsorption behaviour of oligopeptides used in the cosmetic industry onto the components in skin tissue ...
N. Sanjeeva Murthy+3 more
wiley +1 more source
Comparison of ex vivo and in vitro human fibroblast ageing models [PDF]
Several studies have analyzed modulation of gene expression during physiological ageing with interesting, but often contradictory results, depending on the model used.
ANNOVI, Giulia+4 more
core +1 more source
Aging and Altered Gravity: A Cellular Perspective
We propose that, unlike biological aging, where Primary hallmarks initiate damage, spaceflight may trigger a feedback loop between Antagonistic and Integrative hallmarks, driving accelerated aging. Returning to 1 g restores proper signaling and breaks the cycle.
Sharon van Rijthoven+1 more
wiley +1 more source