Results 71 to 80 of about 7,724 (232)

Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

Matrix Biology Plus, 2021
Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in collagen fibers. Type VIII collagen
Amanda L. Mohabeer, Jeffrey T. Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J. Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O. Gramolini, Robert P. Mecham, Scott P. Heximer, Steffen-Sebastian Bolz, Michelle P. Bendeck   +13 more
doaj   +1 more source

Phase behavior and chain dynamics of elastin-like peptides versus amino acid sequences [PDF]

, 2017
Elastin fibrillogenesis is conditioned by multiple self-assembly processes. Previous studies have evidenced the crucial influence of amino acid specificities on molecular organization of glycine-rich elastin-like peptides, but also the important role of ...
Bochicchio, Brigida, Dandurand, Jany, Lacabanne, Colette, Pepe, Antonietta, Samouillan, Valérie   +4 more
core   +3 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Characterization of Endothelial Progenitor Cell Interactions with Human Tropoelastin. [PDF]

PLoS ONE, 2015
The deployment of endovascular implants such as stents in the treatment of cardiovascular disease damages the vascular endothelium, increasing the risk of thrombosis and promoting neointimal hyperplasia.
Young Yu, Steven G Wise, Praveesuda L Michael, Daniel V Bax, Gloria S C Yuen, Matti A Hiob, Giselle C Yeo, Elysse C Filipe, Louise L Dunn, Kim H Chan, Hamid Hajian, David S Celermajer, Anthony S Weiss, Martin K C Ng   +13 more
doaj   +1 more source

Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment

Frontiers in Pharmacology, 2023
Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang, Xinqiang Guan, Lianping He, Xingang Guan, Xingang Guan   +4 more
doaj   +1 more source

Heparan sulfate affects elastin deposition in fibroblasts cultured from donors of different ages [PDF]

, 2012
Heparan sulfate (HS), due to its presence on the cell surface and in the extracellular milieu and its ability to modulate cell signaling, has a fundamental role in both physiological and pathological conditions.
ANNOVI, Giulia, BORALDI, Federica, GUERRA, Deanna, Moscarelli, P., Parma, B., QUAGLINO, Daniela, Sommer, P., TIOZZO, Roberta   +7 more
core   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Glimour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon s Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

UVA Exposure Combined with Glycation of the Dermis Are Two Catalysts for Skin Aging and Promotes a Favorable Environment to the Appearance of Elastosis

Journal of Aging Research, 2021
Skin aging is the result of superimposed intrinsic (individual) and extrinsic (e.g., UV exposure or nutrition) aging. Previous works have reported a relationship between UV irradiation and glycation in the aging process, leading, for example, to modified
Hervé Pageon, Hélène Zucchi, Sylvie Ricois, Philippe Bastien, Daniel Asselineau   +4 more
doaj   +1 more source

Extracellular Matrix Molecules Facilitating Vascular Biointegration [PDF]

, 2014
All vascular implants, including stents, heart valves and graft materials exhibit suboptimal biocompatibility that significantly reduces their clinical efficacy.
Michael, Praveesuda, Ng, Martin K.C., Waterhouse, Anna, Wise, Steven G.   +3 more
core   +1 more source

Biomaterials derived from silk–tropoelastin protein systems [PDF]

Biomaterials, 2010
A structural protein blend system based on silkworm silk fibroin and recombinant human tropoelastin is described. Silk fibroin, a semicrystalline fibrous protein with beta-sheet crystals provides mechanical strength and controllable biodegradation, while tropoelastin, a noncrystallizable elastic protein provides elasticity.
Xiao, Hu, Xiuli, Wang, Jelena, Rnjak, Anthony S, Weiss, David L, Kaplan   +4 more
openaire   +2 more sources