Results 141 to 150 of about 2,662,368 (270)

Proteomics Characterization of Extracellular Space Components in the Human Aorta [PDF]

open access: yes, 2010
The vascular extracellular matrix (ECM) is essential for the structural integrity of the vessel wall and also serves as a substrate for the binding and retention of secreted products of vascular cells as well as molecules coming from the circulation ...
Bregant   +40 more
core   +2 more sources

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova   +10 more
wiley   +1 more source

Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium [PDF]

open access: yes, 2010
One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training.
Adams   +98 more
core   +1 more source

Traditional and Emerging Physical Processing Technologies: Applications and Challenges in Allergen Control of Animal and Plant Proteins

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT Under global food shortages and environmental challenges, the food industry is shifting from animal to plant proteins, coinciding with a rising prevalence of food allergies. Structural and functional differences between animal and plant proteins significantly influence their allergenic potential.
Lili Zhang, Vijaya Raghavan, Jin Wang
wiley   +1 more source

Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review) [PDF]

open access: yes, 2017
The mechanistic complexes of kinase D-interacting substrate of 220 kDa/ankyrin repeat-rich membrane spanning (Kidins220/ARMS) bind and integrate a variety of cellular cues to mediate neuronal activities such as neuronal differentiation, survival, and ...
Cai, Jun   +3 more
core   +1 more source

Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The set‐up and progression of dyskinesia induced by 3,4‐dihydroxyphenylalanine (L‐DOPA) are strongly linked to oxidative stress and neuroinflammation. The aim of this work was to study and characterize the effects of the hydroalcoholic extract of Brazilian red propolis (HERP) on L‐DOPA–induced dyskinesia (LID) in hemiparkinsonian rats injected
Sheilla da Silva Barroso   +9 more
wiley   +1 more source

Cellular mechanisms in sympatho‐modulation of the heart [PDF]

open access: yes, 2017
Cardiovascular function relies on complex servo-controlled regulation mechanisms that involve both fast-acting feedback responses and long-lasting adaptations affecting the gene expression.
Schaub, M. C., Zaugg, M.
core  

The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor [PDF]

open access: yes, 2017
The p75 neurotrophin receptor (p75NTR) and its activation of the sphingomyelin signaling cascade are essential for mechanical hypersensitivity resulting from locally injected nerve growth factor (NGF).
Khodorova, Alla   +2 more
core   +1 more source

Equilibrium Blocking Model of Isometric Tension [PDF]

open access: yesarXiv, 2009
Calcium activation of striated muscle is known to exhibit a strongly cooperative dependency on calcium. Because the calcium receptor protein, troponin (Tn) is known to bind calcium non-cooperatively and has yet to be linked to a cooperative change in the myosin-blocking protein, tropomyosin (Tm), we describe a model in which cooperativity is ...
arxiv  

Cardiac Troponin I Biosensors: Innovations in Real‐Time Diagnosis of Cardiovascular Diseases

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Cardiac troponin I (cTnI) is a crucial biological macromolecule found in the contractile apparatus of cardiac myocytes, exclusively expressed in cardiomyocytes. It is released into the bloodstream upon cardiac tissue injury, serving as a vital biomarker for the early detection of various heart diseases. Despite advancements in cTnI diagnostics
Sara Ebrahimi   +7 more
wiley   +1 more source

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