Results 91 to 100 of about 206,412 (354)

Computational Studies of Cardiac and Skeletal Troponin

Frontiers in Molecular Biosciences, 2019
Troponin is a key regulatory protein in muscle contraction, consisting of three subunits troponin C (TnC), troponin I (TnI), and troponin T (TnT). Calcium association to TnC initiates contraction by causing a series of dynamic and conformational changes ...
Jacob D. Bowman, Steffen Lindert
doaj   +1 more source

Plasma Cardiac Troponin I Concentration and Cardiac Death in Cats with Hypertrophic Cardiomyopathy [PDF]

, 2014
BACKGROUND: The use of cardiac biomarkers to assist in the diagnosis of occult and symptomatic hypertrophic cardiomyopathy (HCM) in cats has been established. There is limited data describing their prognostic utility in cats with HCM.
Abbott, Atkins, Bang, Blume, Chan, Christiaans, Coats, Connolly, Connolly, Connolly, Fernandes, Fox, Fox, Fox, Gersh, Geske, Herndon, Humm, Kittleson, Kubo, Kubo, Langhorn, Lefbom, Lyons, Maron, Maron, Maron, Moreno, Ohno-Machado, Oyama, Paige, Payne, Payne, Peacock, Perna, Perna, Rush, Schober, Schober, Schober, Singletary, Trehiou-Sechi, Wagner, Wess   +43 more
core   +1 more source

Deep learning-enhanced paper-based vertical flow assay for high-sensitivity troponin detection using nanoparticle amplification [PDF]

ACS Nano (2024)
Successful integration of point-of-care testing (POCT) into clinical settings requires improved assay sensitivity and precision to match laboratory standards. Here, we show how innovations in amplified biosensing, imaging, and data processing, coupled with deep learning, can help improve POCT.
arxiv   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Multicenter comparison of four contemporary sensitive troponin immunoassays [PDF]

Journal of Medical Biochemistry, 2014
Background: The IFCC Task Force on Clinical Applications of Cardiac Biomarkers currently recommends evaluation of all troponin immunoassays within the same population to compare their performance. Hence, we planned a multicenter study to compare the four
Luca Salvagno Gian, Giavarina Davide, Meneghello Moira, Musa Roberta, Aloe Rosalia, da Rin Giorgio, Lippi Giuseppe   +6 more
doaj  

Anthracycline-Induced Cardiotoxicity: Cardiac Monitoring by Continuous Wave-Doppler Ultrasound Cardiac Output Monitoring and Correlation to Echocardiography [PDF]

, 2012
Background: Anthracyclines are agents with a well-known cardiotoxicity. The study sought to evaluate the hemodynamic response to an anthracycline using real-time continuous-wave (CW)-Doppler ultrasound cardiac output monitoring (USCOM) and ...
Andreas Hausmann, Cardinale D, Cardinale D, Cardinale D, Cardinale D, Cheitlin MD, Cheitlin MD, Cooper LT, Cooper LT, Dey I, Dorothee Baur, Elliott P, Goorin AM, Gustafsson F, Hans Joachim Stemmler, Iwanaga Y, Jain D, Johanna Tischer, Kinnunen P, Knobloch K, Knobloch K, Knobloch K, Koh E, Lipshultz SE, Meinardi MT, Mueller C, Mueller C, Mueller T, Patricia Suhl, Petra Stieber, Rademaker MT, Ryberg M, Sandra Geiger, Sophia Horster, Steinherz LJ, Stemmler HJ, Tan HL, Urek R, van Lelyveld-Haas LE, Veronika Lange   +39 more
core   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Myocarditis following COVID‐19 vaccine: incidence, presentation, diagnosis, pathophysiology, therapy, and outcomes put into perspective. A clinical consensus document supported by the Heart Failure Association of the European Society of Cardiology (ESC) and the ESC Working Group on Myocardial and Pericardial Diseases

European Journal of Heart Failure, Volume 24, Issue 11, Page 2000-2018, November 2022., 2022
Overview on incidence, diagnosis, and therapy in vaccine‐related myocarditis. CMR, cardiac magnetic resonance; EMB, endomyocardial biopsy; NSAIDS, non‐steroidal anti‐inflammatory drugs. Abstract Over 10 million doses of COVID‐19 vaccines based on RNA technology, viral vectors, recombinant protein, and inactivated virus have been administered worldwide.
Bettina Heidecker, Noa Dagan, Ran Balicer, Urs Eriksson, Giuseppe Rosano, Andrew Coats, Carsten Tschöpe, Sebastian Kelle, Gregory A. Poland, Andrea Frustaci, Karin Klingel, Pilar Martin, Joshua M. Hare, Leslie T. Cooper, Antonis Pantazis, Massimo Imazio, Sanjay Prasad, Thomas F. Lüscher   +17 more
wiley   +1 more source

Specifics of acute coronary syndrome associated with atrial fibrillation in real world clinical practice (based on the registry of the Krasnodar Region)

Alʹmanah Kliničeskoj Mediciny, 2018
Background: Coronary heart disease is the most common cardiovascular disorder, while atrial fibrillation (AF) is the most common heart arrhythmia.Aim: To perform a comparative analysis of the coronary substrate assessed by coronary angiography in ...
Z. G. Tatarintseva, E. D. Kosmacheva, S. A. Raff, S. V. Kruchinova, V. A. Porkhanov   +4 more
doaj   +1 more source

Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]

, 2020
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Linke, Axel, Pfluecke, Christian, Quick, Silvio, Ruf, Tobias F., Strasser, Ruth H., Sveric, Krunoslav M., Troeger, Willi, Wiedemann, Stephan, Winzer, Robert, Youssef, Akram, Zhang, Kun   +14 more
core   +1 more source