Results 91 to 100 of about 276,777 (390)

Measurement of cardiac troponins [PDF]

Annals of Clinical Biochemistry, 2001
The cardiac troponins form part of the regulatory mechanism for muscle contraction. Specific cardiac isoforms of cardiac troponin T and cardiac troponin I exist and commercially available immunoassay systems have been developed for their measurement. A large number of clinical and analytical studies have been performed and the measurement of cardiac ...
David Gaze, Frances Boa, Paul O. Collinson   +2 more
openaire   +3 more sources

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Computational Studies of Cardiac and Skeletal Troponin

Frontiers in Molecular Biosciences, 2019
Troponin is a key regulatory protein in muscle contraction, consisting of three subunits troponin C (TnC), troponin I (TnI), and troponin T (TnT). Calcium association to TnC initiates contraction by causing a series of dynamic and conformational changes ...
Jacob D. Bowman, Steffen Lindert
doaj   +1 more source

Cardiac Troponin I in Patients Undergoing Percutaneous and Surgical Myocardial Revascularization: Comparison of Analytical Methods

Diagnostics, 2023
The myocardial infarction (MI) types 4a and 5 guidelines recommend cardiac troponin (cTn) diagnostic decision limits of 5 and 10 times the 99th percentile, respectively.
Sabrina Pacheco do Amaral Vendramini, Célia Maria Cássaro Strunz, Whady Armindo Hueb, Antonio de Padua Mansur   +3 more
doaj   +1 more source

Proximity mapping of troponin T and troponin I in cardiac troponin using molecular dynamics simulations [PDF]

Biophysical Journal, 2009
The intersite distances from cTnT residues 240, 276, and 288 to cTnI N-terminal residues 5, 17, 27, 40, and to the cTnI C-terminal residues 131, 145, 152, 160, and 167 in reconstituted cTn were determined in the presence of Mg2+ and Mg2+ plus Ca2+ using FRET.
Wen-Ji Dong, Herbert C. Cheung, John M. Robinson, Jun Xing, Jayant James Jayasundar   +4 more
openaire   +2 more sources

Possible mechanisms behind cardiac troponin elevations

Biomarkers, 2018
Cardiac-specific troponins are elevated in blood following cardiac injury and are the preferred diagnostic biomarkers when acute myocardial infarction is suspected clinically.
O. Hammarsten, J. Mair, M. Möckel, B. Lindahl, A. Jaffe   +4 more
semanticscholar   +1 more source

A Comparison of Patient History- and EKG-based Cardiac Risk Scores. [PDF]

, 2019
Patient-specific risk scores are used to identify individuals at elevated risk for cardiovascular disease. Typically, risk scores are based on patient habits and medical history - age, sex, race, smoking behavior, and prior vital signs and diagnoses.
Miller, Andrew C, Mullainathan, Sendhil, Obermeyer, Ziad   +2 more
core  

Label‐Free, Sensitive, and Direct Detection of Cardiac Troponin Biomarkers Using Frequency‐Locked Microring Resonators

Advanced Sensor Research, EarlyView.
A deployable, chip‐integrated approach to the detection of heart attack biomarkers is demonstrated using silicon photonic microring resonators combined with microfluidics. By applying the Pound–Drever–Hall frequency locking technique, sensor signals are measured with improved signal‐to‐noise ratio, applying this to real‐time, selective readouts.
Evan Diamandikos, Tetsuya Shimogaki, Crispin Szydzik, Peter Thurgood, Luke H. Broadley, Sonya Palmer, Guanghui Ren, Thach G. Nguyen, Cesar S. Huertas, Arnan Mitchell   +9 more
wiley   +1 more source

Cardiac Magnetic Resonance Imaging Detects Myocardial Abnormalities in Naturally Infected Dogs with Chronic Asymptomatic Chagas Disease

Animals, 2023
Trypanosoma cruzi infection causes inflammation and fibrosis, resulting in cardiac damage in dogs. The objectives of this study were to describe cardiac magnetic resonance imaging (CMR) in naturally infected dogs with chronic Chagas disease and the ...
Derek J. Matthews, Ryan C. Fries, Nicholas D. Jeffery, Sarah A. Hamer, Ashley B. Saunders   +4 more
doaj   +1 more source

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T [PDF]

International Journal of Biological Sciences, 2006
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation. Isolated rat cardiac myofibrils phosphorylated by PKC/PKA and dephosphorylated by PP1 were used in determining dephosphorylation specificities, Ca(2 ...
Brian H Crawford, Robert L. Raynor, Nathan M. Jideama, A K M A Hussain   +3 more
openaire   +3 more sources