Results 121 to 130 of about 230,788 (365)
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke+36 more
wiley +1 more source
Maria Lucia Mosso,1 Sara Montemerani2 1S.C. Medicina e Chirurgia d’Accettazione ed Urgenza (MeCAU) – Pronto Soccorso, Dipartimento Emergenza Urgenza. Ospedale S.
Mosso ML, Montemerani S
doaj
BackgroundSubclinical myocardial injury, as measured by high‐sensitivity cardiac troponin T (hsTnT), and myocardial stress, as measured by N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), are related to glycemic control in patients with type 2 ...
Pratyaksh K. Srivastava+4 more
doaj +1 more source
The phosphorylation of troponin I from cardiac muscle [PDF]
Heather Cole, S V Perry
openalex +1 more source
Contemporary NSTEMI management: the role of the hospitalist. [PDF]
Non-ST-segment elevation myocardial infarction (NSTEMI) is defined as elevated cardiac biomarkers of necrosis in the absence of persistent ST-segment elevation in the setting of anginal symptoms or other acute event.
Amin, Alpesh+9 more
core +1 more source
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai+16 more
wiley +1 more source
BackgroundIn ST‐segment–elevation myocardial infarction (STEMI), troponins are not needed for diagnosis: symptoms and ECG data are sufficient to activate percutaneous coronary intervention.
Germán Cediel+10 more
doaj +1 more source
The combinational effect of cardiac and biochemical markers in diabetic patients with cardiovascular disease [PDF]
Background: Clinicopathological correlations, as well as several angiographic studies, suggest that diabetic patients have more extensive atherosclerotic disease, affecting the coronary arteries in particular.
Palanisamy Pasupathi, YY Rao, Farook J, Sathiyamoorthy Subramaniyam, Babu Shankar Ponnusha, Athimoolam Ambika, Int J Cur Bio Med Sci.
core
Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang+7 more
wiley +1 more source
Muscle Fatigue from the Perspective of a Single Crossbridge [PDF]
The repeated intense stimulation of skeletal muscle rapidly decreases its force- and motion-generating capacity. This type of fatigue can be temporally correlated with the accumulation of metabolic by-products, including phosphate (Pi) and protons (H ...
Debold, Edward Patrick+3 more
core +1 more source