Results 121 to 130 of about 6,764,388 (368)

A biomarker guided approach in heart failure [PDF]

open access: yes, 2014
Heart failure is one of the commonest diagnoses presenting to physicians in the community or hospital care. Symptoms are often subjective, with clinicians having to rely on clinical assessment and radiological imaging to manage these patients.
Abela, Mark
core  

Probabilistic classification of acute myocardial infarction from multiple cardiac markers [PDF]

open access: yes, 2008
Logistic regression and Gaussian mixture model (GMM) classifiers have been trained to estimate the probability of acute myocardial infarction (AMI) in patients based upon the concentrations of a panel of cardiac markers.
C Bishop   +20 more
core   +1 more source

Calcium-dependent Changes in the Flexibility of the Regulatory Domain of Troponin C in the Troponin Complex*

open access: yesJournal of Biological Chemistry, 2005
With the recent advances in structure determination of the troponin complex, it becomes even more important to understand the dynamics of its components and how they are affected by the presence or absence of Ca2+.
T. Blumenschein   +4 more
semanticscholar   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T

open access: yesInternational Journal of Biological Sciences, 2006
Protein dephosphorylation by protein phosphatase 1 (PP1), acting in concert with protein kinase C (PKC) and protein kinase A (PKA), is a pivotal regulatory mechanism of protein phosphorylation.
doaj  

Effects of Low Cell pH and Elevated Inorganic Phosphate on the pCa-Force Relationship in Single Muscle Fibers at Near-Physiological Temperatures [PDF]

open access: yes, 2014
Intense muscle contraction induces high rates of ATP hydrolysis with resulting increases in Pi, H+, and ADP, factors thought to induce fatigue by interfering with steps in the cross-bridge cycle.
Fitts, Robert H., Nelson, Cassandra R.
core   +2 more sources

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

CLINICAL FEATURES AND DIAGNOSTIC ALGORITHMS OF CARDIOMYOPATHIES WITH RESTRICTIVE PHENOTYPE CAUSED BY CARDIAC TROPONIN I AND DESMIN GENES MUTATIONS

open access: yesПедиатрическая фармакология, 2011
The authors are citing the literature data and share their own experiences of observation of two patients with cardiomyopathy associated with restrictive phenotype caused by mutations in defined genes encoding the synthesis of cardiac troponin I and ...
M.V. Tural'chuk   +2 more
doaj   +2 more sources

Transcriptomic analysis of Ascaris suum larvae during their hepatopulmonary migration [PDF]

open access: yes, 2012
Common roundworms are important intestinal nematodes of man (Ascaris lumbricoides) and pig (Ascaris suum). During the first stages of the infection, the larvae of these parasites undergo a hepatopulmonary migration.
Gasser, Robin   +4 more
core   +1 more source

The side chain of glutamine 13 is the acyl-donor amino acid modified by type 2 transglutaminase in subunit T of the native rabbit skeletal muscle troponin complex. [PDF]

open access: yes, 2013
Subunit T of the native muscle troponin complex is a recognised substrate of transglutaminase both in vitro and in situ with formation of isopeptide bonds.
B. Ura   +9 more
core   +1 more source

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