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Persistent Elevation of Troponin I in a Pediatric Patient Resulting From Macrotroponin Complex.

Pediatrics, 2023
Although chest pain is a common chief complaint among pediatric patients, cardiac pathology historically has accounted for a small percentage of cases.
Matthew R Harberg   +4 more
semanticscholar   +1 more source

The troponin complex and regulation of muscle contraction

The FASEB Journal, 1995
In a wide variety of cellular settings, from organelle transport to muscle contraction, Ca 2+ binding to members of the EF hand family of proteins controls the interaction between actin and different myosins that are responsible for generating movement.
C. Farah, F. Reinach
semanticscholar   +3 more sources

RESOLUTION OF BRAIN TROPONIN COMPLEX

Journal of Neurochemistry, 1979
AbstractAffinity chromatography was used to partially purify the troponin complex from crude regulatory proteins obtained from bovine brain cortex. Three components were obtained from this partially purified troponin complex by treatment with 6 M‐urea and 1 mM‐EGTA followed by chromatography on DEAE‐Sephadex‐A50.
C. Mahendran, S. Berl
semanticscholar   +3 more sources

Physarum tropomyosin-troponin complex. Isolation and properties.

The Journal of Biochemistry, 1975
T. Kato, Y. Tonomura
semanticscholar   +2 more sources

Calcium-induced flexibility changes in the troponin C–troponin I complex

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000
The contraction of vertebrate striated muscle is modulated by Ca(2+) binding to the regulatory protein troponin C (TnC). Ca(2+) binding causes conformational changes in TnC which alter its interaction with the inhibitory protein troponin I (TnI), initiating the regulatory process.
X, Zhao   +6 more
openaire   +2 more sources

Deciphering a macro-troponin I complex; a case report

Clinical Chemistry and Laboratory Medicine (CCLM), 2017
J. Chew-Harris   +4 more
semanticscholar   +3 more sources

Lysine reactivities of tropomyosin complexed with troponin

Archives of Biochemistry and Biophysics, 1988
The relative reactivities of lysine residues of tropomyosin complexed with troponin have been measured in order to locate the binding site of troponin on tropomyosin in a complex between the two native proteins. The lysines were labeled with acetic anhydride using a competitive labeling procedure and the relative reactivities of tropomyosin lysine ...
S E, Hitchcock-DeGregori   +2 more
openaire   +2 more sources

Three-dimensional image reconstruction of actin-tropomyosin complex and actin-tropomyosin-troponin T-troponin I complex

Journal of Molecular Biology, 1975
Abstract The structure of the actin-tropomyosin complex, which represents on active form of the thin filaments of skeletal muscle and the actin-tropomyosin-troponin T-troponin I complex, which represents an inhibited form, have been studied by three-dimensional reconstruction from electron micrographs.
T, Wakabayashi   +3 more
openaire   +2 more sources

Structure of the insect troponin complex.

Journal of molecular biology, 1999
Isolated troponin-tropomyosin complex from Lethocerus indicus asynchronous flight muscle forms paracrystals on a positively charged lipid monolayer. Single particle analysis was carried out on individual complexes selected from electron micrographs of negatively stained paracrystals.
T. Wendt, K. Leonard
semanticscholar   +3 more sources

Proximity relationship in the binary complex formed between troponin I and troponin C

Journal of Molecular Biology, 1986
We have determined six molecular distances among four sites in the binary complex formed between troponin C (TnC) and troponin I (TnI) by fluorescence resonance energy transfer between donor and acceptor probes that were either an intrinsic fluorophore (Trp158 of TnI) or extrinsic probes attached to the sites.
C K, Wang, H C, Cheung
openaire   +2 more sources

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