Results 321 to 330 of about 86,589 (350)

An immunochemical study of the calcium ion-binding protein (troponin-C) and the inhibitory protein (troponin-I) of the troponin complex and their interaction

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1974
1. 1.|Antibodies to troponin-C and troponin-I, prepared by a preparative acrylamide gel electrophoresis, have been studied by Ouchterlony's immunodiffusion procedure. 2. 2.|In amino acid composition and antigenic properties, troponin-C of chicken skeletal muscle resembled the troponin-C from skeletal muscle of other animals more closely than ...
S.V. Perry, T. Hirabayashi
openaire   +3 more sources

Cross-linking of rabbit skeletal muscle troponin subunits: labeling of cysteine-98 of troponin C with 4-maleimidobenzophenone and analysis of products formed in the binary complex with troponin T and the ternary complex with troponins I and T

Biochemistry, 1988
The sulfhydryl-specific, heterobifunctional, photoactivatable cross-linker 4-maleimidobenzophenone (BPMal) was used to study the interaction of rabbit skeletal muscle troponin subunits TnC, TnT, and TnI. TnC was labeled at Cys-98 by the maleimide moiety of BPMal and then mixed with either TnT alone or TnI plus TnT, in the presence of Ca2+.
Terence Tao, John D. Leszyk, Paul C. Leavis, John H. Collins   +3 more
openaire   +3 more sources

Proximity Relationships between Residue 6 of Troponin I and Residues in Troponin C:  Further Evidence for Extended Conformation of Troponin C in the Troponin Complex

Biochemistry, 2000
Skeletal muscle troponin C (TnC) adopts an extended conformation when crystallized alone and a compact one when crystallized with an N-terminal troponin I (TnI) peptide, TnI(1-47) [Vassylyev et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 4847-4852]. The N-terminal region of TnI (residues 1-40) was suggested to play a functional role of facilitating ...
John D. Leszyk, John Gergely, Bing Li, Yin Luo, Terence Tao   +4 more
openaire   +3 more sources

The Crystal Structure of Troponin C in Complex with N-Terminal Fragment of Troponin I

1998
Troponin (Tn), the complex of three subunits (TnC, TnI, and TnT), plays a key role in Ca2+ dependent regulation of muscle contraction. To elucidate the interactions between the Tn subunits and the conformation of TnC in the Tn complex, we have determined the crystal structure of TnC in complex with the N-terminal fragment of TnI (TnI1-7). The structure
Soichi Wakatsuki, Kayo Maeda, Soichi Takeda, Yuichiro Maéda, Dmitry G. Vassylyev   +4 more
openaire   +2 more sources

Phosphorylation and the Regulation of the Function of Myosin and the Troponin Complex

1976
There is now good evidence that three well-characterized enzymes pre-cent in muscle can catalyse the phosphorylation by ATP of proteins of the myofibril (Table 1).
H. A. Cole, A. J. G. Moir, S. V. Perry, N. Frearson, E. Pires, M. Morgan   +5 more
openaire   +2 more sources

Physicochemical studies on the complexes troponin C with troponin T, and reconstituted troponin, and their interaction with calcium ions

Biochemistry, 1974
Rajam S. Mani, Cyril M. Kay, William D. McCubbin   +2 more
openaire   +3 more sources

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

Nature Medicine, 2023
Dimitrios Doudesis, Kuan Ken Lee, Jasper Boeddinghaus   +2 more
exaly  

Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance

European Heart Journal, 2021
Tushar Kotecha, Yousuf Razvi, Kartik Kumar   +2 more
exaly  

High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial

Circulation, 2021
Atul Anand, Andrew R Chapman, Amy V Ferry   +2 more
exaly  

High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain

Circulation, 2022
Yader Sandoval, Fred S Apple, Allan S Jaffe   +2 more
exaly