Results 51 to 60 of about 14,337,199 (401)

A study on elevation of troponin I in ischemic stroke as an independent prognostic marker of outcomes

Nepal Journal of Neuroscience, 2020
Background: Stroke is the second leading cause of death worldwide, comprising approximately 10% of all deaths. A substantial number of stroke patients have elevated cardiac troponin levels and are associated with poorer prognosis.
Pradeep Thapa, Jagdish Prasad Agrawal, Rajani Baniya   +2 more
doaj   +1 more source

Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]

, 2014
Peer ...
Bachmann, M. O., Kwok, C. S., Myint, P. K., Shepstone, L., Stirling, S., Zaman, M. J. S.   +5 more
core   +1 more source

Troponin I

Definitions, 2020
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction.

semanticscholar   +1 more source

Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]

, 2019
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core   +2 more sources

Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T

FEBS Open Bio, 2015
The α‐helix in troponin I (TnI) at the interface with troponin T (TnT) is a highly conserved structure. A point mutation in this region, A116G, was found in human cardiac TnI in a case of cardiomyopathy.
Shirin Akhter, J.-P. Jin
doaj   +1 more source

Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium

European Heart Journal, 2016
Aims Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE ...
S. Blankenberg, V. Salomaa, N. Makarova, F. Ojeda, P. Wild, K. Lackner, T. Jørgensen, B. Thorand, A. Peters, M. Nauck, A. Petersmann, E. Vartiainen, G. Veronesi, P. Brambilla, S. Costanzo, L. Iacoviello, G. Linden, J. Yarnell, C. Patterson, Brendan M. Everett, P. Ridker, J. Kontto, R. Schnabel, W. Koenig, F. Kee, T. Zeller, K. Kuulasmaa   +26 more
semanticscholar   +1 more source

The 99th percentile of reference population for cTnI and cTnT assay: Methodology, pathophysiology and clinical implications [PDF]

, 2017
According to recent international guidelines, including the 2012 Third Universal Definiton of Myocardial Infarction by the Joint ESC/ACCF/AHA/WHF Task Force, an increase in cardiac troponin (cTn) levels over the 99th percentile upper reference limit ...
Clerico, Aldo, Masotti, Silvia, Passino, Claudio, Plebani, Mario, Prontera, Concetta, Ripoli, Andrea, Zaninotto, Martina   +6 more
core   +1 more source

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

Frontiers in Physiology, 2011
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little, Svetlana B Tikunova, Darl R. Swartz, Catalina eNorman, Jonathan P Davis   +4 more
doaj   +1 more source

Combining High-Sensitivity Cardiac Troponin I and Cardiac Troponin T in the Early Diagnosis of Acute Myocardial Infarction

Circulation, 2018
Background: Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a ...
N. H. D. Linden, K. Wildi, R. Twerenbold, J. Pickering, M. Than, L. Cullen, L. Cullen, L. Cullen, J. Greenslade, J. Greenslade, W. Parsonage, W. Parsonage, W. Parsonage, T. Nestelberger, J. Boeddinghaus, P. Badertscher, M. Gimenez, Lieke J. J. Klinkenberg, O. Bekers, A. Schöni, D. Keller, Z. Sabti, C. Puelacher, Janosch Cupa, L. Schumacher, N. Kozhuharov, Karin Grimm, S. Shrestha, D. Flores, M. Freese, C. Stelzig, I. Strebel, Ò. Miró, K. Rentsch, B. Morawiec, D. Kawecki, Wanda Kloos, J. Lohrmann, A. Richards, R. Troughton, C. Pemberton, S. Osswald, M. P. Dieijen-Visser, A. Mingels, T. Reichlin, S. Meex, C. Mueller   +46 more
semanticscholar   +1 more source

Avaliação dos valores séricos de troponina I cardíaca em crianças menores de 1 ano de idade Evaluation of serum cardiac troponin I values in children less than 1 year of age

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto, Werther Brunow de Carvalho   +1 more
doaj   +1 more source