Tissue-specific interactions of TNI isoforms with other TN subunits and tropomyosins in C. elegans: The role of the C- and N-terminal extensions [PDF]
The aim of this study is to investigate the function of the C-terminal extension of three troponin I isoforms, that are unique to the body wall muscles of Caenorhabditis elegans and to understand the molecular interactions within the TN complex between ...
al-Hillawi +35 more
core +1 more source
Cardiac Troponin I Gene Knockout [PDF]
Abstract —Troponin I is a subunit of the thin filament–associated troponin-tropomyosin complex involved in calcium regulation of skeletal and cardiac muscle contraction. We deleted the cardiac isoform of troponin I by using gene targeting in murine embryonic stem cells to determine the developmental and physiological effects of
X, Huang +6 more
openaire +2 more sources
Novel high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome
Background High-sensitivity cardiac troponin assays enable the early risk stratification of patients with suspected acute coronary syndrome to identify those at low risk of myocardial infarction or cardiac death.
A. Chapman +13 more
semanticscholar +1 more source
Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš +15 more
doaj +1 more source
Prognostic value of troponin I after coronary artery bypass grafting (AMIRI-CABG study)
In 2017, the European Society of Cardiology outlined the importance of the problem of diagnosing myocardial ischemia-reperfusion injury following coronary artery bypass grafting.
N. S. Bunenkov +6 more
doaj +1 more source
Background: Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a ...
N. H. D. Linden +46 more
semanticscholar +1 more source
Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core +2 more sources
Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]
Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen +34 more
core +4 more sources
Cerebral hypoperfusion during cardiopulmonary bypass surgery has been thought to be a factor in the aetiology of brain damage with evidence of post operative neurological deficits.
Nozeihan Jan Bappu +3 more
doaj +1 more source
Inverted Takotsubo Syndrome With HELLP Syndrome: A Case Report
BackgroundTakotsubo syndrome is an acute cardiac condition involving sudden, transient apical ballooning of the left ventricle of the heart that may be triggered by emotional stress and some non-cardiac conditions.
Paul Gabarre +15 more
doaj +1 more source

