Results 81 to 90 of about 160,167 (306)

Troponin and anti-troponin autoantibody levels in patients with ventricular noncompaction. [PDF]

PLoS ONE, 2013
Ventricular hypertrabeculation/noncompaction is a morphologic and functional anomaly of myocardium characterized by prominent trabeculae accompanied by deep recessus.
Hatice Betül Erer, Tolga Sinan Güvenç, Ahu Sarbay Kemik, Hale Yaka Yılmaz, Şeref Kul, Servet Altay, Nurten Sayar, Yüksel Kaya, Mehmet Eren   +8 more
doaj   +1 more source

Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes [PDF]

, 2017
Background: Sodium glucose co-transporter 2 (SGLT2) inhibitors may reduce cardiovascular and heart failure risk in patients with type 2 diabetes mellitus (T2DM).
Butler, Javed, Davies, Michael J., Desai, Mehul, Januzzi, James L., Jarolim, Petr, Sattar, Naveed, Vijapurkar, Ujjwala   +6 more
core   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

Advanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li, Jia‐Hui Huang, Jin‐E Yang, Yi‐Hang Li, Juan‐Zhen Hong, Ting‐Ting Wang, Ying‐Lei Chi, Meng‐Zhi Wu, Wei Wang, Ying Zhu, Shi‐Mei Zhuang   +10 more
wiley   +1 more source

Troponin-I as a Prognostic Marker in Patients with Coronavirus Disease 2019: Insights from a Single-center Investigation

Current Medical Issues
Background: Troponin-I is conventionally correlated with myocardial injury, but its relevance in assessing the severity of coronavirus disease 2019 (COVID-19) and its implications for patient management remains an area of ongoing investigation.
Dany John, Ramesh Kawade, Abhijeet B Shelke   +2 more
doaj   +1 more source

Is high sensitive-troponin I a reliable biomarker for cardiac injury in methadone toxicity? A prospective cross-sectional study

BMC Pharmacology and Toxicology, 2022
Background Methadone is a synthetic opioid mostly used for detoxification therapy, as its use increases; the possibility for methadone-induced cardiotoxicity may rise.
Hasan Shemirani, Masoumeh Sadeghi, Azadeh Davoudian Dehkordi, Farzad Gheshlaghi   +3 more
doaj   +1 more source

High-sensitivity cardiac troponin T and copeptin assays to improve diagnostic accuracy of exercise stress test in patients with suspected coronary artery disease [PDF]

, 2014
Background: The average diagnostic sensitivity of exercise stress tests (ESTs) is lower than that of other non-invasive cardiac stress tests. The aim of the study was to examine whether high-sensitivity cardiac troponin T (hs-cTnT) or copeptin ...
Dörr, Oliver, Gaede, Luise, Hamm, Christian W., Hoffmann, Jedrzej, Liebetrau, Christoph, Möllmann, Helge, Nef, Holger M., Rolf, Andreas, Weber, Michael, Wolter, Jan S.   +9 more
core   +1 more source

Cardiac Troponin I in Racing Standardbreds [PDF]

Journal of Veterinary Internal Medicine, 2012
BackgroundUpper reference limits forcTnIhave not been established for healthy Standardbred racehorses.ObjectivesTo establishcTnIupper reference limits for Standardbred racehorses and determine if increases in plasmacTnIconcentration can be detected in 1–2 hours after a race.AnimalsSamples were obtained from 586 apparently healthy Standardbreds aged 2 ...
J, Slack, R C, Boston, L, Soma, V B, Reef   +3 more
openaire   +2 more sources

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Comparison of point-of-care and laboratory troponin I assays

Zdravniški Vestnik, 2011
BACKGROUND In recent years a number of pointof- care troponin assays have emerged. There have been reports of discrepancies between the results of point-of-care and laboratory assays.
Andrej Markota, Matej Bernhardt, Miroslav Palfy   +2 more
doaj  

Real‐Time Digital Micromotor Tracking‐Enabled Ultrasensitive Immunoassay

Advanced Science, EarlyView.
An AI‐facilitated real‐time digital micromotor tracking‐enabled immunoassay is developed, which leverages a self‐developed multi‐microparticle tracking system to monitor micromotor motion trajectories in a real‐time manner for digital protein analysis.
Jingjing Shi, Zuhua Yu, Hui Tian, Wenjiao Fan, Yuanyuan Sun, Wei Ren, Chenghui Liu   +6 more
wiley   +1 more source