Results 81 to 90 of about 14,082,843 (400)

Improvement of outcome prediction of hospitalized patients with COVID-19 by a dual marker strategy using high-sensitive cardiac troponin I and copeptin [PDF]

, 2021
C. Kaufmann, Amro Ahmed, Mona Kassem, MKF Freynhofer, Bregje Jaeger, Gabriele Aicher, Susanne Equiluz‐Bruck, Alexandra Spiel, Florian Vafai-Tabrizi, Michael Gschwantler, Peter Fasching, J W Wojta, Evangelos Giannitsis, Klaus Huber   +13 more
openalex   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Use of Cardiac Biomarkers for Monitoring Improvement of Left Ventricular Function by Immunoadsorption Treatment in Dilated Cardiomyopathy

Biomolecules, 2019
Immunoadsorption and subsequent administration of intravenous immunoglobulin (IVIG) have shown beneficial effects on cardiac function and symptoms in patients with dilated cardiomyopathy. Biomarkers play an emerging role in disease monitoring and outcome
Karolina Weinmann, Jakob Werner, Wolfgang Koenig, Wolfgang Rottbauer, Daniel Walcher, Mirjam Keßler   +5 more
doaj   +1 more source

Assessment of the Relationship between Mortality and Troponin I Levels in Hospitalized Patients with the Novel Coronavirus (COVID-19)

Medicina, 2020
Background and Objectives: This study aimed to evaluate the relationship between mortality and cardiac laboratory findings in patients who were hospitalized after a positive PCR for COVID-19 infection.
Sinem Özyılmaz, Esra Ergün Alış, Emrah Ermiş, Samir Allahverdiyev, Hakan Uçar   +4 more
doaj   +1 more source

Influence of case definition on incidence and outcome of acute coronary syndromes [PDF]

, 2016
© 2016, BMJ Publishing Group. All rights reserved. Objective: Acute coronary syndromes (ACS) are common, but their incidence and outcome might depend greatly on how data are collected.
Alamgir, Farqad, Atkin, Paul, Clark, Andrew L, Cleland, John G F, Goode, Kevin, Hoye, Angela, Kilpatrick, Eric, Panahi, Hossein, Rigby, Alan, Sherwi, Nasser, Thackray, Simon, Torabi, Azam   +11 more
core   +2 more sources

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Prognostic prediction of troponins in cardiac myxoma: case study with literature review

Brazilian Journal of Cardiovascular Surgery, 2015
Objective:It was supposed that troponins in cardiac myxoma patients might be in a same fashion as in the conditions without myocardial injury. In order to verify this hypothesis, troponins in cardiac myxoma patients were discussed by presenting a ...
Shi-Min Yuan
doaj   +1 more source

Proteolytic Digestion of Serum Cardiac Troponin I as Marker of Ischemic Severity.

The Journal of Applied Laboratory Medicine, 2018
BACKGROUND The serum troponin assay is the biochemical gold standard for detecting myocardial infarction (MI). A major diagnostic issue is that some believe troponin levels can rise with reversible injury, in the absence of radiologically detectable ...
Somaya Zahran, V. Figueiredo, M. Graham, R. Schulz, P. Hwang   +4 more
semanticscholar   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

High sensitive TROponin levels In Patients with Chest pain and kidney disease:a multicenter registry: The TROPIC study [PDF]

, 2017
  Background: Accuracy of high sensitive troponin (hs-cTn) to detect coronary artery disease (CAD) in patients with renal insufficiency is not established.
Ballocca, Flavia, Bergerone, Serena, Biondi Zoccai, Giuseppe, Budano, Carlo, D'Ascenzo, Fabrizio, Della Riva, Diego, di Cuia, Marco, Diletti, Roberto, Dudek, Dariusz, Dziewierz, Artur, Ferenbach, David, Gaita, Fiorenzo, Galassi, Alfredo, Jan van Geuns, Robert, Mariani, Andrea, Marra, Sebastiano, Mieghem, Nicolas M, Mills, Nick L., Moretti, Claudio, Omedè, Pierluigi, Palazzuoli, Alberto, Palmerini, Tullio, Pavani, Marco, Reed, Matthew J., Van Domburgh, Ron T, Zijlstra, Felix   +25 more
core   +3 more sources