Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
ESC Heart Failure, EarlyView.Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna +4 more
wiley +1 more source
Characterization of pig skeletal muscle transcriptomes in response to low temperature
Veterinary Medicine and Science, Volume 9, Issue 1, Page 181-190, January 2023., 2023 Low temperature changes the gene expression pattern and biological pathway in pig skeletal muscle. Under low temperature, biological pathways of lipid, amino acid, and carbohydrate metabolism; signal transduction; endocrine, immune, and nervous system; cardiovascular disease; infectious diseases caused by bacteria or viruses; and neurodegenerative ...
DongJie Zhang +4 more
wiley +1 more source
Influence of cellular mechano-calcium feedback in numerical models of cardiac electromechanics [PDF]
arXivMultiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysical processes to balance fidelity and computational cost. In this work, we propose an eikonal-based framework that incorporates mechano-calcium feedback -- the effect of ...
arxiv
Impact of soluble fms-like tyrosine kinase-1 and placental growth factor serum levels for risk stratification and early diagnosis in patients with suspected acute myocardial infarction [PDF]
, 2017 Aims Angiogenic factors play an important role in the development of atherosclerosis and show pronounced changes during acute myocardial infarction (AMI). We analysed the impact of placental growth factor (PlGF) and its endogen opponent, soluble fms-like
Breidthardt, Tobias +11 more
core
Impact on clinical guideline adherence of Orient-COVID, a CDSS based on dynamic medical decision trees for COVID19 management: a randomized simulation trial [PDF]
arXivBackground: The adherence of clinicians to clinical practice guidelines is known to be low, including for the management of COVID-19, due to their difficult use at the point of care and their complexity. Clinical decision support systems have been proposed to implement guidelines and improve adherence.
arxiv
Deficiencies of myocardial troponin-T and creatine kinase MB isoenzyme in dogs with idiopathic dilated cardiomyopathy [PDF]
, 1997 Peter J. O’Brien
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Clinical characteristics and long‐term outcomes in patients with apical hypertrophic cardiomyopathy
ESC Heart Failure, EarlyView.Abstract Aims As a special type of hypertrophic cardiomyopathy (HCM), apical HCM (ApHCM) has different clinical characteristics while its nature history and prognosis are not well recognized. We aimed to describe the characteristics and outcomes of ApHCM and identify predictors of adverse outcomes.
Meng Guo +3 more
wiley +1 more source
Linchuang shenzangbing zazhiObjectiveTo determine the variation of troponin T （TnT） in diabetic kidney disease （DKD） patients treated with dialysis， and to evaluate its clinical value.MethodsA total of 8，553 DKD patients treated with dialysis and examination of TnT values were ...
Yu Rui +5 more
doaj +1 more source
RNA Expression of Cardiac Troponin T Isoforms in Diseased Human Skeletal Muscle [PDF]
, 1999 Vincent Ricchiuti, Fred S. Apple
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